[Lormetazepam in the treatment of sleep disorders in a medical practice; double-blind test on 100 patients (author's transl)].

Abstract

Lormetazepam (1 mg) and diazepam (5 mg) were compared in a double-blind study of 100 patients with sleep disorders associated with a medical illness. Assignment to one of two treatment groups was at random. Lormetazepam had a greater hypnotic effect than diazepam in all significant variables (P less than 0.05). There was no hangover effect or other side effects with lormetazepam, which was thus superior to diazepam also in this respect (P less than 0.05).

• Authors: H D Hentschel, M Sastre y Hernández, K Fichte
• Journal: Deutsche medizinische Wochenschrift (1946) (Dtsch Med Wochenschr) Vol. 106 Issue 22 Pg. 711-4 (May 29 1981) ISSN: 0012-0472 [Print] Germany
• Vernacular Title: Lormetazepam bei der Behandlung von Schlafstörungen in der internistischen Praxis. Doppelblindprüfung an 100 Patienten.
• PMID: 6113127 (Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Anti-Anxiety Agents
• Benzodiazepines
• lormetazepam
• Lorazepam
• Diazepam

Topics

• Adult
• Aged
• Anti-Anxiety Agents (therapeutic use)
• Benzodiazepines
• Diazepam (adverse effects, therapeutic use)
• Double-Blind Method
• Female
• Humans
• Lorazepam (analogs & derivatives, therapeutic use)
• Male
• Middle Aged
• Sleep Wake Disorders (drug therapy)