Facilitation of development of resistance to morphine analgesia by desglycinamide9-lysine vasopressin.

Abstract	Desglycinamide(9)-lysine vasopressin facilitates development of resistance to the analgesic action of morphine in mice if morphine is administered before the peptide. Desglycinamide(9)-lysine vasopressin is not a morphine antagonist, and does not appear to cause either hyperalgesia or alteration of the response to the technique used for evaluating analgesia.
Authors	W A Krivoy, E Zimmermann, S Lande
Journal	Proceedings of the National Academy of Sciences of the United States of America (Proc Natl Acad Sci U S A) Vol. 71 Issue 5 Pg. 1852-6 (May 1974) ISSN: 0027-8424 [Print] United States
PMID	4525467 (Publication Type: Journal Article)
Chemical References	Amides Analgesics Peptides Vasopressins Morphine Lysine Glycine
Topics	Amides Analgesics Animals Drug Resistance Female Glycine Lysine Mice Mice, Inbred Strains Morphine Peptides (pharmacology) Reaction Time (drug effects) Vasopressins (pharmacology)

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