This experiment was carried out to investigate the effect of combined treatment of
tubal obstruction infertility with deacetylated
chitosan and two microscopes on the levels of IFN-γ and
ICAM-1. In this study, 100 infertile patients with fallopian tube obstruction who were treated in Jiangbei District Hospital of
traditional Chinese medicine from January to August 2019 were divided into two groups according to the alternating grouping method, group A (50 cases) received combined surgery, and Group B (50 cases) received combined surgery and
chitosan. The curative effect and postoperative pelvic adhesion of the two groups were analyzed, and the levels of IFN-γ,
ICAM-1 and IL6(IL-6),
laminin (LN),
Transforming growth factor beta 1(TGF-β1) and
fibronectin (FN) were observed before and
after treatment. Results showed that the total effective rate of Group B was higher than that of Group A (92. 00% vs 76. 00%). The incidence of pelvic adhesion was lower in Group A (4. 00% vs 16. 00%) (P < 0.05). The levels of IFN-γ,
ICAM-1,
IL-6, LN, FN and TGF-β1 in Group B were significantly lower than those in group A (P < 0.05). In conclusion, the treatment of
tubal obstruction infertility with combined deacetylated
chitosan and biendoscopy is effective, which can reduce the levels of IFN-γ and
ICAM-1, improve the expression of adhesion-related factors and reduce the occurrence of pelvic adhesion.