Abstract | INTRODUCTION: AREAS COVERED: The mechanism of action of tranexamic acid and novel delivery systems for its topical delivery have been discussed. Further, patents related to the topical delivery of tranexamic acid and clinical trials undertaken to analyze their potential have been discussed. EXPERT OPINION: Targeting tranexamic acid in the epidermal layer makes more amount of drug available for action on melanocytes, the target site for tranexamic acid. Novel drug delivery formulations like liposomes, solid lipid nanoparticles, nano-lipidic carriers, and topical beads have the potential of achieving epidermal targeting. Epidermal targeting of tranexamic acid can help in the superior delivery of the drug, making its topical treatment more efficient.
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Authors | Piyush Verma, Khushwant S Yadav |
Journal | Expert opinion on drug delivery
(Expert Opin Drug Deliv)
Vol. 20
Issue 6
Pg. 773-783
(06 2023)
ISSN: 1744-7593 [Electronic] England |
PMID | 37086183
(Publication Type: Journal Article)
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Chemical References |
- Tranexamic Acid
- Liposomes
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Topics |
- Humans
- Tranexamic Acid
(therapeutic use)
- Administration, Cutaneous
- Liposomes
- Hyperpigmentation
(drug therapy)
- Skin
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