Materials and Methods: This is a Prospective longitudinal study including 34 patients diagnosed with acute
invasive fungal infection by contrast enhancement magnetic resonance imaging studies of paranasal, orbit and brain or nasal biopsy for KOH/culture. Diagnosis is made through routine blood tests, biopsy, and radiological imaging. The patients taken for the study were
COVID-19 reverse transcription-polymerase chain reaction positive or recent post
COVID-19 (within 15 days) or symptoms of
COVID-19 with bilateral
pneumonitis. The study was conducted with 34 patients admitted to the department of medicine with
mucormycosis within a month may 2021.
Results: A total of 34 patients with a mean age of 50.92 years old and male female ratio 24/10 (70.5/29.41) were included in this study. The most common comorbidity was
diabetes mellitus (23 patients 67.64%). Nine patients were newly diagnosed or recent onset of diabetes with or after
COVID-19 infection. Twenty-four (70.58%) patients were
COVID-19 positive or recent (within 15 days) history of
COVID-19 positive. Seven (20.58) patients had the history of
steroid as a treatment during
COVID-19 and 5 (14.70) patients was on
oxygen inhalation. One (2.94%) patient was fully vaccinated, and 5 (14.70) patients had the history of
steam inhalation. The most common involvement was naso-orbital
mucormycosis found in 28 patients (82.35%) followed by nasal-and orbital 26 (76.47) and 18 (52.94), respectively. Naso-Orbito-Cerebral was seen in 16 (47.05) patients. The more common reported symptoms and signs were
headache (76.47), facial
numbness (64.70), Nasal discharge (52.94), and
ophthalmoplegia (52.94). Cranial nerve involvement was seen in 10 patients (
facial palsy in 8 patients and
bulbar palsy in 2 patients). Total mortality was 7 (7/34 20.58%).
Conclusion: