Abstract | BACKGROUND: METHODS: A retrospective study was conducted based on 261 cases of mid-pregnancy termination in our hospital, where 34 cases with placenta previa were set as the observation group, and the remaining 227 cases were set as control group. At first, the termination method of Mifepristone combined with Misoprostol/ Ethacridine Lactate was adopted. If the volume of prenatal bleeding was up to 400 mL, emergency uterine artery embolization (UAE) was implemented to stop bleeding, then cervical double balloon (CDB) was used to promote cervical ripening. Receiver operating characteristic (ROC) curves analysis was performed to assess the accuracy in predicting the length of placental edge crossed the cervical os for prenatal bleeding. RESULTS: The number of gravidity/parities, the rate of cesarean section, the medical cost, the rate of previous cesarean section were all higher in the observation group than in the control group (P < .05). The volume of prenatal hemorrhage, postpartum hemorrhage, the rate of puerperal morbidity, emergency UAE rate and ICU rate were higher in the observation group than in the control group (P < .05). There were 4 cases showing prenatal hemorrhage up to 400 mL and undergoing emergency UAE + CDB in the observation group, while there were no such cases in the control group (P < .05). An optimal cut-off value of 1.7cm for the length of placental edge crossed the cervical os in diagnosing prenatal hemorrhage demonstrated sensitivity and specificity of 75.0% and 86.7%, respectively (area under the ROC curve, 0.858). CONCLUSION:
|
Authors | Qingyun Long, Shiyao Wu, Shuguo Du, Ruyan Li, Yun Zhao, Fei Tang |
Journal | Medicine
(Medicine (Baltimore))
Vol. 101
Issue 31
Pg. e29908
(Aug 05 2022)
ISSN: 1536-5964 [Electronic] United States |
PMID | 35945718
(Publication Type: Journal Article)
|
Copyright | Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. |
Chemical References |
- Misoprostol
- Mifepristone
- Ethacridine
|
Topics |
- Cesarean Section
- Ethacridine
- Female
- Humans
- Mifepristone
- Misoprostol
- Placenta
- Placenta Previa
(therapy)
- Pregnancy
- Retrospective Studies
|