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Pathomechanisms of AERD-Recent Advances.

Abstract
The pathomechanisms behind NSAID-exacerbated respiratory disease are complex and still largely unknown. They are presumed to involve genetic predisposition and environmental triggers that lead to dysregulation of fatty acid and lipid metabolism, altered cellular interactions involving transmetabolism, and continuous and chronic inflammation in the respiratory track. Here, we go through the recent advances on the topic and sum up the current understanding of the background of this illness that broadly effects the patients' lives.
AuthorsAnnina Lyly, Tanya M Laidlaw, Marie Lundberg
JournalFrontiers in allergy (Front Allergy) Vol. 2 Pg. 734733 ( 2021) ISSN: 2673-6101 [Electronic] Switzerland
PMID35387030 (Publication Type: Journal Article, Review)
CopyrightCopyright © 2021 Lyly, Laidlaw and Lundberg.

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