Granulomatous mastitis: An underdiagnosed inflammatory disease afflicting minority women.

Abstract

Granulomatous mastitis (GM) is an underdiagnosed and understudied benign inflammatory disease of the breast whose accurate diagnosis is confounded by mimicry of other breast pathologies (infectious mastitis and abscess, malignancy) and limited clinician knowledge of the disease. GM disproportionately affects minority women, furthering health disparities for a demographic already disadvantaged in the care of breast diseases. The first step in diagnosis is ultrasound followed by core needle biopsy yielding granulomatous inflammation. To far lesser degree, mammography, and MRI may play a role in narrowing the differential. A high index of clinical suspicion and multidisciplinary approach is required. The presence of Corynebacterium kroppensteddti may indicate one subtype of granulomatous mastitis called cystic neutrophilic granulomatous mastitis; disease stratification, and individualized therapy are on the horizon.

• Authors: Daniel R Bacon, Smith M Ngeve, Sheryl G Jordan
• Journal: Radiology case reports (Radiol Case Rep) Vol. 16 Issue 12 Pg. 3990-3994 (Dec 2021) ISSN: 1930-0433 [Print] Netherlands
• PMID: 34745405 (Publication Type: Case Reports)
• Copyright: © 2021 The Authors. Published by Elsevier Inc. on behalf of University of Washington.