Abstract | BACKGROUND: METHODS: We conducted a retrospective cohort study of adult GBS patients admitted to the Philippine General Hospital from 2009 to 2019. RESULTS: We included 105 patients with confirmed GBS diagnoses. The median age was 43 years (interquartile range 32 to 56); the female-to-male ratio was 1.62:1; the predominant variant was acute inflammatory demyelinating polyneuropathy (n = 40, 38.1%). The difference in outcomes of patients in the IVIg (n = 44) and TPE (n = 24) groups (walking with aid/GBS-disability scores/ ventilator dependency at 1 month, duration dependent on the ventilator, intensive care unit stay, and hospital stay) were not statistically significant, except for mild disability at 1 month (p = 0.009). Pneumonia, urinary tract infection, and dysautonomia were significantly related to a prolonged hospital stay. No predetermined variables were associated with late motor recovery. After adjusting for age and sex, the cumulative hazard risk for late motor recovery was 0.69 (95% CI 0.27-1.74). CONCLUSION: Our study presented the first comprehensive information regarding the features and outcomes of GBS patients in the Philippines. ABBREVIATIONS:
|
Authors | Adrian I Espiritu, Karl Josef Niño J Separa, Francis Jordan C Milla, Karen Joy B Adiao, Carl Froilan D Leochico, Roland Dominic G Jamora |
Journal | Neurological research
(Neurol Res)
Vol. 43
Issue 12
Pg. 995-1004
(Dec 2021)
ISSN: 1743-1328 [Electronic] England |
PMID | 34229572
(Publication Type: Journal Article)
|
Chemical References |
- Immunoglobulins, Intravenous
|
Topics |
- Adult
- Cohort Studies
- Disability Evaluation
- Female
- Guillain-Barre Syndrome
(complications, therapy)
- Humans
- Immunoglobulins, Intravenous
(therapeutic use)
- Male
- Middle Aged
- Philippines
- Plasma Exchange
(methods)
- Recovery of Function
- Retrospective Studies
|