Abstract | INTRODUCTION: AREAS COVERED: This perspective evaluates recent clinical trials of nonopioids, opioids, and combination therapy for use in acute pain. Acetaminophen and nonsteroidal anti-inflammatory drugs ( NSAIDs) often provide adequate analgesia, although these agents are not without risks. Combination therapy using a small amount of opioid together with a nonopioid pain reliever has been shown effective and reduces opioid consumption. EXPERT OPINION:
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Authors | Joseph V Pergolizzi, Peter Magnusson, Jo Ann LeQuang, Frank Breve, Robert Taylor, Charles Wollmuth, Giustino Varrassi |
Journal | Expert opinion on pharmacotherapy
(Expert Opin Pharmacother)
Vol. 22
Issue 9
Pg. 1119-1126
(Jun 2021)
ISSN: 1744-7666 [Electronic] England |
PMID | 33689517
(Publication Type: Journal Article)
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Chemical References |
- Analgesics, Non-Narcotic
- Analgesics, Opioid
- Anti-Inflammatory Agents, Non-Steroidal
- Acetaminophen
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Topics |
- Acetaminophen
(therapeutic use)
- Acute Pain
(drug therapy)
- Analgesics, Non-Narcotic
(therapeutic use)
- Analgesics, Opioid
(therapeutic use)
- Anti-Inflammatory Agents, Non-Steroidal
(therapeutic use)
- Humans
- Pain, Postoperative
(drug therapy)
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