Abstract | PURPOSE: Cancer survivors treated with stem-cell transplant (SCT) and radiation therapy are at a high risk for late effects including the metabolic syndrome. This study reviewed the prevalence of the metabolic syndrome in pediatric central nervous system (CNS) tumor survivors treated with autologous SCT and craniospinal radiation. METHODS: RESULTS: CONCLUSION: Pediatric CNS tumor survivors treated with autologous SCT and craniospinal radiation are at risk for early signs of metabolic syndrome, most commonly hyperlipidemia. Further studies evaluating the progression of these early signs to full criteria for the metabolic syndrome diagnosis are required.
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Authors | Chantel Cacciotti, Muhammad Ali, Ute Bartels, Jonathan D Wasserman, Erilda Kapllani, Joerg Krueger, Eric Bouffet, Tal Schechter |
Journal | Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
(Childs Nerv Syst)
Vol. 37
Issue 4
Pg. 1087-1094
(04 2021)
ISSN: 1433-0350 [Electronic] Germany |
PMID | 33205297
(Publication Type: Journal Article)
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Topics |
- Central Nervous System Neoplasms
- Child
- Cross-Sectional Studies
- Hematopoietic Stem Cell Transplantation
- Humans
- Metabolic Syndrome
(diagnosis, epidemiology, etiology)
- Prospective Studies
- Risk Factors
- Survivors
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