Abstract | BACKGROUND: METHODS: 39 MD patients were recruited in the study. First, 0.1 ml of 20-fold diluted gadolinium- diethylenetriamine acid ( Gd-DTPA) was delivered onto the posterior upper part of the tympanic medial wall using a soft-tipped micro-irrigation catheter through an artificially perforated tympanic membrane. Inner ear MRI was performed 24 h after Gd-DTPA administration using a 3T MR machine and a 20-channel head/neck coil with an 8 min sequence of medium inversion time inversion recovery imaging with magnitude reconstruction (MIIRMR). The parameters were as follows: TR 16000 ms, TE 663 ms, inversion time 2700 ms, flip angle 180°, slices per slab 60. RESULTS: Efficient inner ear uptake of Gd-DTPA was detected 24 h after delivery and it created excellent contrast in the inner ear of all cases. High quality images demonstrating EH in the vestibule and cochlea were obtained. CONCLUSION: Targeted delivery of minimum Gd-DTPA (0.1 ml, 20-fold dilution) onto the posterior upper portion of the tympanic medial wall and MRI with MIIRMR in a 3T machine and 20-channel head/neck coil are clinically practical to obtain high quality images displaying EH.
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Authors | Jing Zou, Zhen Wang, Yukun Chen, Guoping Zhang, Luguang Chen, Jianping Lu |
Journal | World journal of otorhinolaryngology - head and neck surgery
(World J Otorhinolaryngol Head Neck Surg)
Vol. 5
Issue 4
Pg. 180-187
(Dec 2019)
ISSN: 2589-1081 [Electronic] United States |
PMID | 32083244
(Publication Type: Journal Article)
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Copyright | © 2019 The Authors. |