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Gadolinium DTPA (Magnevist)

Subscribe to New Research on Gadolinium DTPA

A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see PENTETIC ACID), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)

Also Known As:

Magnevist; Gadopentetic Acid; Gadopentetate Dimeglumine; Berlex Brand of Gadopentetate Dimeglumine; Gadolinium DTPA Dimeglumine; Gadolinium DTPA Dimeglumine Salt; Gadolinium DTPA Disodium Salt; Gadolinium Diethylenetriaminepenta-acetic Acid; Juste Brand of Gadopentetate Dimeglumine; Magnevist Enteral; Magnograf; Magnograf Enteral; Schering Brand of Gadopentetate Dimeglumine; DTPA, Gadolinium; Diethylenetriaminepenta-acetic Acid, Gadolinium; Dimeglumine, Gadolinium DTPA; Dimeglumine, Gadopentetate; Gadolinium Diethylenetriaminepenta acetic Acid; Gd DTPA; Gd-DTPA

Networked: 2047 relevant articles (138 outcomes, 267 trials/studies)

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Drug Context: Research Results

Experts

1.	Rofstad, Einar K: 21 articles (10/2014 - 08/2004)
2.	Ewing, James R: 12 articles (11/2014 - 08/2003)
3.	Naganawa, Shinji: 10 articles (02/2011 - 03/2006)
4.	Nakashima, Tsutomu: 9 articles (02/2011 - 01/2008)
5.	Benjaminsen, Ilana C: 9 articles (11/2008 - 08/2004)
6.	Ellingsen, Christine: 8 articles (10/2014 - 03/2009)
7.	Nagaraja, Tavarekere N: 8 articles (10/2014 - 08/2003)
8.	Knight, Robert A: 8 articles (01/2014 - 08/2003)
9.	Runge, Val M: 8 articles (03/2011 - 07/2002)
10.	Sone, Michihiko: 8 articles (02/2011 - 01/2008)

Related Diseases

1.	Neoplasms (Cancer) 12/01/1988 - "In most cases, Gd-DTPA-enhanced T1-weighted spin-echo scans best delineated tumor margins, and the enhancement was helpful in suggesting a cellular or active nature of the lesions. " 05/01/1998 - "High-resolution contrast-enhanced (Gd-DTPA) dynamic MR imaging in cervical cancer offers improved tumor/cervical-stroma contrast and provides useful information on parametrial invasion." 07/01/1992 - "To investigate the efficacy of 0.025, 0.05 and 0.1 mmol/kg gadopentetate dimeglumine in MR imaging of patients with intracranial tumors at mid and high field strength. " 07/01/1990 - "We present examples of the significantly improved soft tissue contrast with Gd-DTPA T1-weighted images and discuss the improved tumor margin definition with Gd-DTPA. " 04/01/1989 - "Liposomal Gd-DTPA caused significant improvement in contrast between liver and tumor (P less than .005) on T1-weighted MR images. "
2.	Neoplasm Metastasis (Metastasis) 08/01/1986 - "Our studies suggest a significant potential for improved detection of liver metastases with Gadolinium-DTPA-enhanced liver MRI." 04/01/1989 - "Liposomal Gd-DTPA-enhanced images permitted significant improvement in metastasis detection by five blinded radiologists (P less than .005). " 05/01/2014 - "The aim of this study was to compare the diagnostic performance of gadopentetate dimeglumine and gadoxetic-acid-enhanced MRI in patients with colorectal liver metastases. " 11/01/1996 - "The results of the study provide evidence that the use of magnevist enhances the informative value and specificity of MRT in the diagnosis of spinal metastases." 04/01/2015 - "Small numbers of brain metastases were enhancing when first detected by MRI and remained enhancing, whereas other metastases remained nonenhancing to Gd-DTPA throughout the experiment. "
3.	Hepatocellular Carcinoma (Hepatoma) 12/01/2010 - "This study compared the efficacy of gadoxetic acid-enhanced MRI and gadopentetate dimeglumine-enhanced MRI in the detection of small hepatocellular carcinoma (HCC). " 12/01/2010 - "Diagnostic efficacy of gadoxetic acid-enhanced MRI in the detection of hepatocellular carcinomas: comparison with gadopentetate dimeglumine." 03/01/1995 - "Basic analysis of dynamic study in cases of hepatocellular carcinoma using inversion recovery snap shot FLASH MR imaging with Gd-DTPA." 02/01/2015 - "To compare gadopentetate dimeglumine and gadoxetic acid-enhanced magnetic resonance imaging (MRI) for image quality and hepatocellular carcinoma (HCC) detection/conspicuity. " 10/20/2005 - "In phantoms, in which T(1) values (44-191 msec) were assumed to be shortened by the effect of Gd-DTPA in hepatocellular carcinoma (HCC), the highest SNR in each phantom was observed at FA ranging from 15 to 30 degrees. "
4.	Acoustic Neuroma (Acoustic Neurinoma) 03/01/1999 - "The purpose of this work was to assess the changes of signal intensity on constructive interference in steady state (CISS) 3D Fourier transformation (3DFT) MRI after administration of Gd-DTPA and to evaluate the efficacy of contrast-enhanced CISS-3DFT MRI to depict the seventh and eighth cranial nerves affected by vestibular schwannomas. " 11/01/1994 - "The current gold standard for diagnosing vestibular schwannomas is MRI with gadolinium-DTPA enhancement. " 08/01/1989 - "The use of Gd-DTPA improved the quality of the MR images by markedly enhancing the acoustic tumors in all cases. " 01/01/1988 - "Clinical advantages of Gd-DTPA include shorter scan times, macroscopic tumour/oedema separation and improved detection of certain tumours, particularly acoustic neuromas." 01/01/1992 - "The fate of tumour rests following removal of acoustic neuromas: an MRI Gd-DTPA study."
5.	Carcinoma (Carcinomatosis) 06/01/1996 - "The conspicuity of 12 of 13 carcinomas was improved in postcontrast MT-FLASH imaging enables excellent visualization of Gd-DTPA-enhancing breast lesions." 11/01/2000 - "With gadopentetate dimeglumine, the mean values for fPV and PEV were significantly greater in carcinomas (P <. " 08/01/1991 - "[The diagnosis of bladder carcinomas by NMR tomography: an improvement with Gd-DTPA?]." 06/01/2003 - "The study included 43 patients with biopsy-proven prostate carcinoma: 28 were examined by 1.0-T MRI (Turbo-FLASH) and 15 by 1.5-T MRI (FLASH) with infusion of 0.1 mmol/kg Gd-DTPA. " 05/01/1996 - "The purpose of this study is to compare the usefulness of conventional MR imaging and gadopentetate dimeglumine enhanced fat-suppressed MR imaging for the depiction and staging of rectal carcinoma. "

Related Drugs and Biologics

1.	Gadolinium DTPA (Magnevist)
2.	Gadolinium
3.	gadobenic acid (gadobenate dimeglumine)
4.	Pentetic Acid (DTPA)
5.	gadobutrol
6.	Contrast Media
7.	Cystamine
8.	gadodiamide (Omniscan)
9.	Liposomes (Liposome)
10.	ferumoxides (Feridex)

Related Therapies and Procedures

1.	Intravenous Injections
2.	Stents
3.	Radiotherapy
4.	Diskectomy (Discectomy)
5.	Intravenous Infusions