Aortic Arch Aneurysm in Behçet Disease Successfully Treated with Infliximab.

Abstract

Aortic arch aneurysm (AAA) is a rare involvement in Behçet disease (BD). It is often life-threatening, yet few reports related to the treatment of AAA have been published. We herein report a 27-year-old woman with AAA caused by vascular BD. She was initially treated with prednisolone 1 mg/kg/d. However, the inflammation had not subsided after three weeks, so infliximab (IFX) was added for relief. After IFX administration, the C-reactive protein level normalized, and computed tomography at three months after therapeutic intervention revealed that the aneurysm had disappeared. This case suggests that early induction of IFX might be effective for aortic aneurysm in BD.

• Authors: Taihei Nishiyama, Yuya Kondo, Shota Okamoto, Mayu Terasaki, Hirofumi Toko, Mizuki Yagishita, Hiroyuki Takahashi, Masahiro Yokosawa, Hiroto Tsuboi, Isao Matsumoto, Takayuki Sumida
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 59 Issue 8 Pg. 1087-1091 (Apr 15 2020) ISSN: 1349-7235 [Electronic] Japan
• PMID: 31915317 (Publication Type: Case Reports, Journal Article)

Chemical References

• Infliximab

Topics

• Adult
• Aorta, Thoracic (pathology)
• Aortic Aneurysm (complications)
• Behcet Syndrome (complications, drug therapy)
• Female
• Humans
• Infliximab (therapeutic use)
• Tomography, X-Ray Computed
• Treatment Outcome