Prednisolone (Predate)

A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.

Also Known As:

Networked: 8159 relevant articles (1193 outcomes, 880 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Kohno, Shigeru: 20 articles (01/2014 - 07/2002)
2.	Pieters, Rob: 14 articles (06/2015 - 08/2004)
3.	Moriwaki, Hisataka: 14 articles (10/2013 - 01/2002)
4.	Kawakami, Atsushi: 12 articles (01/2015 - 01/2004)
5.	Tanaka, Hiroshi: 12 articles (12/2012 - 12/2002)
6.	Matsuda, Masayuki: 12 articles (01/2012 - 05/2002)
7.	Hashimoto, Takashi: 11 articles (11/2013 - 01/2004)
8.	Tsurumi, Hisashi: 11 articles (10/2013 - 06/2002)
9.	Kasahara, Senji: 11 articles (10/2013 - 06/2002)
10.	Origuchi, Tomoki: 10 articles (01/2015 - 01/2004)

Related Diseases

1.	Nephrotic Syndrome (Syndrome, Nephrotic) 09/01/2007 - "After receiving systemic anticoagulant therapy and oral prednisolone, his neurological symptoms improved dramatically, and complete remission from nephrotic syndrome was achieved. " 01/01/2013 - "30 pediatric patients with steroid sensitive nephrotic syndrome were studied; known as SSNS at complete remission or low dose of Prednisolone and have relapse on follow up. " 09/01/2003 - "Prednisolone therapy induced complete remission of nephrotic syndrome. " 01/01/2009 - "Treatment of adult MCD with low prednisolone dose and CsA seems to be equally effective with high prednisolone dose to induce remission of nephrotic syndrome. " 09/01/2006 - "The nephrotic syndrome was treated successfully with prednisolone. "
2.	Proteinuria 03/01/2011 - "Intensive treatment with a combination of methyl prednisolone pulse therapy and oral prednisolone was successful in achieving complete remission and disappearance of proteinuria in our patient." 05/01/2003 - "Of the 60 patients, 20 cases (33.3%) (Group 1) reached a complete remission of proteinuria by prednisolone alone. " 08/01/1989 - "Clinically, those patients were divided into four stages as follows: (1) untreated nephrotic stage, (2) prednisolone (PSL) treated nephrotic stage, (3) persistent proteinuria stage (incomplete remission, ICR), and (4) complete remission (CR). " 04/03/1987 - "In the 4 cases with complete remission of proteinuria prednisolone was tapered. " 01/01/2006 - "Maximal proteinuria, total amount of BCL, BCL exposure time, and use of prednisolone or other immunosuppressant agents did not significantly influence time until remission. "
3.	Asthma (Bronchial Asthma) 01/01/2013 - "Prednisolone therapy induced rapid symptom remission, which was achieved within one month from the onset of asthma to the diagnosis of CSS. " 12/01/2003 - "There was a significant improvement after oral prednisolone compared with placebo in FEV1, ml (mean difference, 237; 95% confidence intervals, 43, 231; p = 0.019), morning PEF L/m (mean difference, 36.8; 95% confidence intervals (CI), 11, 62; p = 0.006), and asthma control score (mean difference, -0.72; 95% CI, -1.2, -0.3; p = 0.004) in never-smokers with asthma but no change in smokers with asthma (mean differences of 47, 6.5, and -0.05 with p values of 0.605, 0.47, and 0.865, respectively). " 09/15/2008 - "To determine whether a 5-day course of oral prednisolone is superior to a 3-day course in reducing the 2-week morbidity of children with asthma exacerbations who are not hospitalised. " 10/01/2005 - "The purpose of this study was to evaluate the additive efficacy of intravenous prednisolone in a randomized controlled study in the management of infants and toddlers with acute severe asthma. " 03/01/2003 - "Therefore, the aim of this study was to evaluate the anti-inflammatory efficacy of 1.8-cineol by determining its prednisolone equivalent potency in patients with severe asthma. "
4.	Inflammation 05/01/2009 - "Modulation of the innate immune response in TNF(ARE/+) mice by the late administration of prednisolone resulted in a significant improvement in survival and decreased cardiac inflammation, whereas early administration of prednisolone resulted in a blunted innate response and increased mortality in littermate control mice. " 04/01/2009 - "Importantly, as demonstrated by successful therapy with prednisolone, the chronic TMA-induced CHS model, in contrast to acute and subacute models, made prolonged therapeutic treatment of a pre-established skin inflammation possible. " 01/01/1962 - "[Good results in the treatment of toxic inflammation with intravenous prednisolone]." 11/01/2008 - "Histologic assessment showed prednisolone-treated mice (62%) had a higher rate of clearance of middle and inner ear inflammation than control mice (4%). " 07/01/1988 - "This confirms that such low dose prednisolone therapy is effective in controlling joint inflammation."
5.	Rheumatoid Arthritis 04/01/2009 - "To evaluate if remission induced by low-dose prednisolone during the first 2 years of rheumatoid arthritis (RA) in the BARFOT glucocorticoid (GC) study had a sustained effect on radiological damage for a total of 4 years. " 03/14/1998 - "To determine whether short-term, oral low dose prednisolone (< or = 15 mg daily) is superior to placebo and non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis. " 02/01/1975 - "Since for various reasons the Lansbury Index appeared inadequate to define the therapeutic efficacy of antirheumatic compounds, we chose to investigate in our trials the prednisolone saving effect in patients with rheumatoid arthritis. " 02/01/2007 - "An elemental diet for 2 weeks resulted in a clinical improvement in patients with active rheumatoid arthritis, and was as effective as a course of oral prednisolone 15 mg daily in improving subjective clinical parameters. " 11/01/2005 - "Low-dose prednisolone in addition to the initial disease-modifying antirheumatic drug in patients with early active rheumatoid arthritis reduces joint destruction and increases the remission rate: a two-year randomized trial."

Related Drugs and Biologics

1.	Cyclophosphamide (Cytoxan)
2.	Vincristine (Oncovin)
3.	Doxorubicin (Adriamycin)
4.	Cyclosporine (Ciclosporin)
5.	Methylprednisolone
6.	Azathioprine (Imuran)
7.	rituximab (Mabthera)
8.	Dexamethasone (Maxidex)
9.	Methotrexate (Mexate)
10.	Prednisone (Sone)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Aftercare (After-Treatment)
3.	Combination Drug Therapy (Combination Chemotherapy)
4.	Oral Administration
5.	Enema (Enemas)