Effort-reward imbalance at work is associated with hair cortisol concentrations: Prospective evidence from the Dresden Burnout Study.

Abstract

Chronic stress experienced at work is considered a major health challenge for modern societies. In fact there is ample evidence that deleterious work environments, based on high efforts in relation to few rewards, substantially augment the risk for a number of highly prevalent diseases (e.g. ischemic heart disease, stroke). One potential pathway mediating these associations involves the stress-related activation of the hypothalamus-pituitary-adrenocortical (HPA) axis with proceeding alterations in the secretion of its main effector hormone cortisol. In this study we assessed a prospective, two-year effect of effort-reward imbalance (ERI) on cortisol secretion, based on a sub sample (N = 150; mean ± SD age: 42.4 ± 11.1; 84.0% female) of the ongoing Dresden Burnout Study (DBS). The provided ERI measures were collected as part of the online baseline and first follow up assessment. Further, cortisol secretion patterns over prolonged periods of time were evaluated in three consecutive years of laboratory baseline and follow up visits. Our findings suggest prospective associations between ERI and cortisol, indicating a blunted cortisol secretion in response to long-term work stress (p < 0.001). Given the regulatory properties of cortisol on various central and peripheral target tissues (e.g. cardiovascular system, liver, adipose tissue), a long-term decrease of cortisol availability can be hypothesized to cause multiple health-challenging consequences. Based on our findings, providing work environments where high efforts are always linked with high rewards have to be considered an important issue for employees health.

• Authors: Marlene Penz, Johannes Siegrist, Magdalena K Wekenborg, Nicole Rothe, Andreas Walther, Clemens Kirschbaum
• Journal: Psychoneuroendocrinology (Psychoneuroendocrinology) Vol. 109 Pg. 104399 (11 2019) ISSN: 1873-3360 [Electronic] England
• PMID: 31394489 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2019 Elsevier Ltd. All rights reserved.

Chemical References

• Hydrocortisone

Topics

• Adult
• Burnout, Professional (metabolism, psychology)
• Burnout, Psychological (psychology)
• Female
• Hair (chemistry)
• Humans
• Hydrocortisone (metabolism)
• Hypothalamo-Hypophyseal System (metabolism)
• Longitudinal Studies
• Male
• Middle Aged
• Occupational Health
• Occupational Stress (metabolism)
• Pituitary-Adrenal System (metabolism)
• Prospective Studies
• Reward
• Stress, Psychological (metabolism)
• Surveys and Questionnaires
• Workplace (psychology)