Limited auricular relapsing polychondritis in a child treated successfully with infliximab.

Abstract

Relapsing polychondritis (RP) is a rare progressive and destructive multisystem disorder characterised by recurrent inflammation of cartilaginous structures. It is a rare disease in paediatrics compared with adults. In children, the diagnosis is either delayed or overlooked due to low incidence. Auricular chondritis has been described in more than half of paediatric cases with RP. However, isolated auricular chondritis has not been reported as the only presentation of pediatric-onset RP. We described a lad who presented with isolated auricular chondritis, which is refractory to conventional treatment, including glucocorticoids and methotrexate as steroid-sparing agent. Remission of his disease's relapses was sustained with infliximab. Limited auricular involvement as a presenting feature of RP in the absence of systemic association is very rare in children. We describe a case of successful use of infliximab on limited auricular chondritis disease.

• Authors: Jubran Theeb Alqanatish, Basma Ali Alfarhan, Sara Mohammed Qubaiban
• Journal: BMJ case reports (BMJ Case Rep) Vol. 12 Issue 5 (May 23 2019) ISSN: 1757-790X [Electronic] England
• PMID: 31126928 (Publication Type: Case Reports, Journal Article)
• Copyright: © BMJ Publishing Group Limited 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Chemical References

• Antirheumatic Agents
• Infliximab

Topics

• Adolescent
• Antirheumatic Agents (administration & dosage, therapeutic use)
• Diagnosis, Differential
• Ear Auricle
• Humans
• Infliximab (administration & dosage, therapeutic use)
• Male
• Polychondritis, Relapsing (diagnosis, drug therapy, pathology)