Abstract | CONTEXT: In the resource poor country like India it is difficult to get HLA screening and EMA testing in patients with celiac disease in small centres. AIMS: SETTINGS AND DESIGN: This was a prospective study conducted in the department of paediatrics of a tertiary referral hospital in north India in 3 stages viz. on presentation, after 3 months and 6 months of initial presentation. MATERIALS AND METHODS: 392 patients with symptoms suggestive of celiac disease were screened for IgA tTG levels more than 10 folds of upper limit of normal. 50 cases (who followed up for 6 months regularly) were enrolled in the study. Spectrum of various growth and clinical parameters were also studied. Statistical analysis used: Statistical analysis was performed by the SPSS version 20.0. Data were checked for normality before statistical analysis. p value less than 0.05 was considered statistically significant. RESULTS: 50 cases were enrolled in study. After initiation of gluten free diet, improvements were seen in various growth factors like height (12.71%) and weight (3.47 cm) after 6 months. Serum tTG( IgA) levels decreased to 94.88±55.35 U/mL from baseline level of 202±83.96 U/mL after 6 months. CONCLUSIONS:
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Authors | Dayanand Hota, Kapil Bhalla, Sanjiv Nanda, Ashish Gupta, Shuchi Mehra |
Journal | Journal of family medicine and primary care
(J Family Med Prim Care)
Vol. 8
Issue 3
Pg. 823-827
(Mar 2019)
ISSN: 2249-4863 [Print] India |
PMID | 31041208
(Publication Type: Journal Article)
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