Pregnancy-Induced Sweet's Syndrome Treated with Infliximab.

Abstract

OBJECTIVE:

To present a case of relapsing and resistant Sweet's syndrome that developed during pregnancy together with an onset of Crohn's disease, showing complete resolution with the use of infliximab.

CLINICAL PRESENTATION AND INTERVENTION:

A 30-year-old pregnant woman presented with fever, skin lesions, and diarrhea. Skin biopsy confirmed neutrophilic dermatosis and she was diagnosed with Crohn's disease after endoscopy. There was no recurrence of Sweet's syndrome outside of her pregnancy. During a previous pregnancy, while corticosteroids were ineffective, complete regression of skin lesions was achieved using infliximab.

CONCLUSION:

The "off-label" use of infliximab is beneficial for relapsing and resistant Sweet's syndrome.

• Authors: Brigita D Smolovic, Mirjana D Gajic-Veljic, Milos M Nikolic, Damir F Muhovic
• Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre (Med Princ Pract) Vol. 28 Issue 2 Pg. 196-198 ( 2019) ISSN: 1423-0151 [Electronic] Switzerland
• PMID: 30376667 (Publication Type: Case Reports)
• Copyright: © 2018 The Author(s) Published by S. Karger AG, Basel.

Chemical References

• Dermatologic Agents
• Infliximab

Topics

• Adult
• Dermatologic Agents (therapeutic use)
• Female
• Humans
• Infliximab (therapeutic use)
• Pregnancy
• Pregnancy Complications (drug therapy)
• Sweet Syndrome (diagnosis, drug therapy)