Abstract | BACKGROUND/AIMS: METHODS: RESULTS: We enrolled 92 subjects, including 60 with IBS-D and 32 healthy controls. The percentages of patients with IgE-mediated serological food hypersensitivity were not significantly different between the groups (controls = 28.1% and IBS-D = 33.3%). Serum IL-1β, IL-6, IL-8, macrophage inflammatory protein-1alpha, and TNF-α levels were higher in patients with IBS-D than in controls. Serum concentration of TNF-α (43.4 vs 21.8 pg/mL, P = 0.009) was higher in patients with IBS-D without IgE-mediated serological food hypersensitivity than those with food hypersensitivity. CONCLUSIONS:
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Authors | Ryo Katsumata, Manabu Ishii, Suni Lee, Yukiko Handa, Takahisa Murao, Minoru Fujita, Hiroshi Matsumoto, Takemi Otsuki, Akiko Shiotani |
Journal | Journal of neurogastroenterology and motility
(J Neurogastroenterol Motil)
Vol. 24
Issue 3
Pg. 415-421
(Jul 30 2018)
ISSN: 2093-0879 [Print] Korea (South) |
PMID | 29739174
(Publication Type: Journal Article)
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