HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Immunoglobulin E (IgE)

An immunoglobulin associated with MAST CELLS. Overexpression has been associated with allergic hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).
Also Known As:
IgE; E, Immunoglobulin; Immunoglobulins, E
Networked: 19487 relevant articles (602 outcomes, 1986 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Valenta, Rudolf: 82 articles (10/2015 - 02/2002)
2. Sampson, Hugh A: 66 articles (12/2015 - 04/2002)
3. Park, Hae-Sim: 57 articles (06/2015 - 05/2002)
4. Valenta, R: 48 articles (10/2015 - 01/2000)
5. Vieths, Stefan: 45 articles (03/2015 - 01/2002)
6. Hamilton, Robert G: 40 articles (11/2015 - 08/2002)
7. Platts-Mills, Thomas A E: 38 articles (11/2015 - 03/2002)
8. Wahn, U: 34 articles (08/2015 - 03/2000)
9. Burks, A Wesley: 32 articles (05/2015 - 01/2002)
10. Galli, Stephen J: 31 articles (10/2015 - 06/2002)

Related Diseases

1. Hypersensitivity (Allergy)
2. Asthma (Bronchial Asthma)
03/01/1999 - "This study suggests that (1) the percentage of CD4+, CD8+, or IL-2R+ lymphocytes in peripheral blood was significantly elevated during acute attacks and returned to normal ranges after complete remission was achieved; (2) plasma soluble IL-2R is a sensitive marker for asthma activity; and (3) atopic asthmatic children seem to have a hereditary predisposition of having higher levels of soluble IL-2R in asthma attacks, coinherited with the trait of IgE."
01/01/2012 - "Blood immunoglobulin E levels were significantly increased in the asthma group, and blood eosinophils were significantly elevated in the complete asthma remission, symptomatic remission and asthma groups compared with controls. "
07/01/2000 - "I have three objectives: (1) review T cell differentiation leading to the Th1/Th2 paradigm; (2) evaluate the increased prevalence of atopy, including asthma, as a consequence of a Th2-dominated immune system; (3) relate the high prevalence of asthma in inner city United States black children to the relatively recent migration of their ancestors from tropical regions of Africa, where genetically biased Th2-dependent IgE responses may be important in protection against high burdens of parasitic worms."
06/01/2015 - "Our study indicates that dust mite SLIT therapy was effective in reducing asthma symptoms and in increasing sIgG4 but did not significantly reduce medication scores or specific D pteronyssinus IgE levels. "
10/01/2015 - "The geometric mean serum free IgE level at 24 weeks was 15.6 ng/mL. Compared with baseline, total asthma symptom scores, daily activity scores and nocturnal sleep scores at 24 weeks were significantly improved. "
3. Infection
4. Atopic Dermatitis (Atopic Eczema)
5. Rhinitis

Related Drugs and Biologics

1. Antibodies
2. Immunoglobulin G (IgG)
3. Immunoglobulin E (IgE)
4. omalizumab (Xolair)
5. Antigens
6. Allergens
7. anti-IgE
8. Cytokines
9. Interleukin-13
10. Immunoglobulin A (IgA)

Related Therapies and Procedures

1. Immunotherapy
2. Oral Administration
3. Drug Therapy (Chemotherapy)
4. Intranasal Administration
5. Injections