From January 2012 to March 2015, 135 cases AMI complicated with
arrhythmia in our hospital were divided into 2 groups: 70 cases in the AMI uncomplicated with
arrhythmia and 65 cases in the AMI complicated with
arrhythmia. 62 cases volunteers accepted physical examination in our hospital in the same period were collected as the control group. 24 hour-electrocardiogram detected by ambulatory electrocardiogram (AECG), SOD and MDA in peripheral blood detected by
diagnostic reagent kit and Na+-K+-
ATP enzymes in peripheral blood detected by
malachite green Kit Method
phosphate determination method were collected. ROC curve was used to evaluate the prognostic value of SOD, MDA and Na+-K+-
ATP enzymes in AMI patients.
RESULTS: Compared with the control group, the patients had unusual ambulatory electrocardiography had increased (P <0.05), peripheral blood SOD and Na+-K+-
ATP enzymes had decreased, peripheral blood MDA had increased in 2 AMI groups (P <0.05). Compared with AMI uncomplicated with
arrhythmia group, the patients had unusual ambulatory electrocardiography had increased (P <0.05), peripheral blood SOD and Na+-K+-
ATP enzymes had decreased, peripheral blood MDA had increased in AMI complicated with
arrhythmia group (P <0.05). Among 135 cases AMI patients, 120 (88.9%) survived and 15 (11.1%) died, of whom 11 cases were AMI complicated with
arrhythmia group, 4 cases were AMI uncomplicated with
arrhythmia group. Compared with the AMI uncomplicated with
arrhythmia group, the dead patients were more in the AMI complicated with
arrhythmia group (c2 = 4.287, P = 0.038). Compared with the survival group, the SOD and Na+-K+-
ATP enzymes were significantly lower (P <0.05) and MDA significantly higher (P <0.05) in the death group. The area under the ROC curve of SOD, MDA and Na+-K+-
ATP enzymes were 0.958, 0.954 and 0.993 respectively, and the cut-off values were 30.66 ng/ml, 576.70 nmol/ml and 57.42 nmol/mgh, respectively.
CONCLUSION: Ambulatory electrocardiography has a close relationship with the peripheral blood SOD, MDA and Na+-K+-
ATP enzymes in AMI patients complicated with
arrhythmia, which might predict AMI condition.