Therapeutic Ultrasound and Prostate Cancer.

Abstract

Therapeutic ultrasound approaches including high-intensity focused ultrasound (HIFU) are emerging as popular minimally invasive alternative treatments for localized, low-to-intermediate risk prostate cancer. FDA approval was recently granted for two ultrasound-guided HIFU devices. Clinical trials for devices using MRI guidance are ongoing. The current level of evidence for whole-gland ultrasound ablation suggests that its clinical efficacy and adverse event rates including erectile dysfunction and urinary incontinence are similar to current definitive therapies such as radical prostatectomy and external-beam radiotherapy. Short-term data suggest that more focal therapy could reduce the rates of adverse events.

• Authors: Karthik M Sundaram, Sam S Chang, David F Penson, Sandeep Arora
• Journal: Seminars in interventional radiology (Semin Intervent Radiol) Vol. 34 Issue 2 Pg. 187-200 (Jun 2017) ISSN: 0739-9529 [Print] United States
• PMID: 28579687 (Publication Type: Journal Article, Review)