Erectile Dysfunction

10/01/2009 - "Sildenafil citrate 50 mg is the recommended starting dose for men with erectile dysfunction (ED); however, most men are later titrated to sildenafil 100 mg for improved efficacy. "
08/01/2005 - "Sildenafil, a highly selective inhibitor of PDE 5, is effective in the treatment of erectile dysfunction. "
07/01/2005 - "Most of the available data on efficacy for sildenafil are based on a questionnaire and erectile dysfunction (ED) is classified with minor or severe organic factors. "
12/20/2000 - "In most patients with good sleep efficiency and who have erectile dysfunction, sildenafil, rather than a placebo, taken at bedtime produces a significantly improved nocturnal erectile activity. "
07/01/2000 - "Sildenafil is highly effective for treating erectile dysfunction (ED). "

03/01/2013 - "All patients were satisfied with postoperative penile length while shortening of the penis was noted in 13 patients 
(40%) with median penile length loss of 1.5 cm. In addition, no de novo erectile dysfunction was observed, and sexual function was significantly improved evidenced by the IIEF-5 scores, especially in the patients who have received PDE5 inhibitors for two months after two weeks surgery. "
01/01/2021 - "Phosphodiesterase-type 5 inhibitors (PDE5i) are the recommended first-line treatment for erectile dysfunction. "
01/01/2016 - "Phosphodiesterase type 5 inhibitors (PDE5Is) are the leading drugs for the treatment of erectile dysfunction (ED), being recommended as a first line treatment by both the European and US urological guidelines. "
03/01/2011 - "Although improved nerve-sparing techniques have reduced the incidence of nerve injury, and the administration of phosphodiesterase type 5 inhibitors has revolutionized the treatment of erectile dysfunction, this problem remains a considerable challenge. "
03/01/2006 - "It has been demonstrated that both the steric and electrostatic factors should appropriately be taken into account in future rational design and development of more active and more selective PDE5 inhibitors for the therapeutic treatment of erectile dysfunction (ED)."

01/01/2013 - "Tadalafil showed good efficacy and safety for improving LUTS and erectile dysfunction in men with BPH, and 5 mg of tadalafil significantly improved Qmax."
11/01/2012 - "Tadalafil significantly improved treatment satisfaction on the Erectile Dysfunction Inventory of Treatment Satisfaction (P < .001 vs placebo at end point) and psychosocial outcomes on the Self-Esteem and Relationship (SEAR) questionnaire (least squares mean difference in SEAR total score change from baseline, 11.8 [95% confidence interval, 5.4%-18.2%; P < .001 vs placebo]). "
11/01/2011 - "Tadalafil significantly improved the International Index of Erectile Function-Erectile Function score in sexually active men with erectile dysfunction (ED; 6.7 vs 2.0; p<0.001) at 12 wk (not assessed at week 1). "
10/01/2008 - "Tadalafil (2.5 mg) significantly improved the International Prostate Symptom Score obstructive subscore and the International Index of Erectile Function-Erectile Function domain, the latter in sexually active men with a history of erectile dysfunction. "
06/01/2006 - "Compared with placebo, tadalafil significantly improved erectile dysfunction on all efficacy outcomes (P < 0.001). "

07/02/2019 - "Even if oral type 5 phosphodiesterase inhibitors (PDE5i) seem an effective treatment for erectile dysfunction (ED), the drop-out is high among patients. "
08/01/2018 - " with phosphodiesterase-5 inhibitors, which are well established in the treatment of erectile dysfunction (ED) gives significant improvement in LUTS and post-void residual and can therefore be recommended for patients with LUTS and ED.Phytotherapies"
02/01/2013 - "Phosphodiesterase type 5 (PDE-5) inhibitors are effective for the treatment of erectile dysfunction (ED), and large-scale epidemiologic studies suggest a strong link between LUTS and ED. "
12/01/2006 - "The advent of oral phosphodiesterase type 5 (PDE-5) inhibitors, however, has greatly enhanced erectile dysfunction treatment; patients have demonstrated high tolerability and success rates for improved erectile function. "
05/01/2024 - "Positively, phosphodiesterase-5 inhibitors appear effective for treating erectile dysfunction and improving sexual quality of life in MwMS. "

11/01/2010 - "Vardenafil (levitra, Bayer Schering Pharna, Germany) is a 5-phosphodiesterase inhibitor which proved highly effective and safe in the treatment of erectile dysfunction. "
01/01/2006 - "Vardenafil was well tolerated and highly efficacious in men with erectile dysfunction and untreated mild major depression. "
01/01/2012 - "The efficacy of on-demand vardenafil ODT 10 mg was established in the POTENT I and II studies, which were 6-week, randomized, double-blind, multinational trials in men with erectile dysfunction of at least 6 months duration. "
06/01/2005 - "In this difficult to treat population of men with erectile dysfunction subsequent to NS-RRP on demand treatment with vardenafil during a 3-month period significantly improved key aspects of the sexual experience important to patient quality of life."
01/01/2002 - "In a large, placebo-controlled trial in patients with mild to severe erectile dysfunction (ED), vardenafil 5, 10 or 20mg taken as needed over a 12-week period significantly improved the scores in questions 3 and 4 of the International Index of Erectile Function (IIEF). "

12/01/2000 - "MUSE was effective and safe in most patients with erectile dysfunction in this study. "
08/01/2001 - "Although MUSE is an appropriate and safe treatment for many patients with erectile dysfunction, the lack of consistency is a significant consideration. "
12/01/1993 - "PGE1 is effective in inducing artificial penile erection and it has a role in the diagnosis and treatment of erectile dysfunction, it is considered to be a more suitable agent than other vasoactive drugs."
12/01/2005 - "Intracavernous injection of prostaglandin E1 is effective in patients with erectile dysfunction not responding to phosphodiseterase 5 inhibitors."
04/01/2003 - "PGE1 cream is an effective, safe and well-tolerated treatment in subjects with erectile dysfunction of organic, psychologic or mixed etiology."

03/01/2003 - "Patients given testosterone supplementation experienced a subjective improvement in their wellbeing, but reported no significant improvement in their erectile dysfunction. "
04/01/2001 - "Topical treatment with cream containing testosterone and vasoactive agents may represent a new effective treatment for erectile dysfunction associating with aging."
01/01/2023 - "Preoperative testosterone <2.3 ng ml-1 was an independent predictor of improvement in erectile dysfunction. "
11/01/2017 - "The available literature supports a role for TTh in men with low testosterone levels, erectile dysfunction, and low libido, with symptomatic improvement in these men."
01/01/2017 - "Men with erectile dysfunction (IIEF-5⩽20) had improved erectile function with testosterone treatment. "

10/01/1991 - "The findings suggest that I-C papaverine, although effective in treating impotence, is not a panacea, and a large percentage of users (55% in our study) are likely to discontinue the drug within a relatively short period of time."
01/01/1992 - "The results suggest that measurement of corporal clearance of Tc-RBC after intracorporal injection of papaverine may be a useful method in detecting venous leak, and could be used as a screening test in patients with erectile dysfunction."
02/01/1995 - "This study was done as a phase I, placebo controlled, nonblinded investigation of the safety and efficacy of a topical papaverine gel in the treatment of erectile dysfunction. "
02/01/1990 - "Five patients recovered from erectile dysfunction and 1 patient showed papaverine-induced full erection. "
01/01/1990 - "A simple test to predict the outcome of intracavernous papaverine treatment would be helpful in the management of erectile dysfunction. "

01/01/2017 - "Overall, surgical penile lengthening procedures at time of IPP insertion appear safe and effective for treatment of patients with penile shortening and severe erectile dysfunction. "
04/01/1997 - "Early results suggest that outpatient IPP insertion is a safe, effective treatment for men with organic impotence."
03/01/2015 - "Penoscrotal IPP surgical techniques that have improved outcomes and advanced the field of prosthetic urology for the treatment of medically refractive erectile dysfunction are presented. "
10/01/2020 - "This study shows no significant increase in risk of surgical complication in patients exposed to pelvic RT and supports the use of IPP in men with a history of RT and refractory erectile dysfunction."
01/16/2019 - "A total of 342 patients with erectile dysfunction who underwent AMS 700 LGX IPP implantation between October 2014 and April 2016 were included in this study. "

03/01/2002 - "To determine the risk-benefit ratio of a forced dose-escalation regimen (2 to 3 to 4 mg) in a European clinical study evaluating apomorphine sublingual (SL) in treating erectile dysfunction (ED), by evaluating the overall tolerability and efficacy of the regimen compared with placebo in patients with ED, and evaluating efficacy by assessing the proportion of successful attempts resulting in sexual intercourse. "
05/01/1998 - "Four of the patients reported erectile dysfunction before beginning apomorphine and two of these report a significant improvement in their sexual function resulting from apomorphine use. "
10/01/2001 - "Sublingual (SL) apomorphine (2 to 6 mg) has been shown to be effective for treatment of male erectile dysfunction. "
08/01/2001 - "The development process for apomorphine SL as an effective treatment for patients with erectile dysfunction has been somewhat unusual. "
01/01/2001 - "Apomorphine SL (Ixense, Uprima) is a new oral medication shown to be effective in the treatment of erectile dysfunction. "

05/19/2022 - "Shockwave Therapy for Erectile Dysfunction: Which Gives the Best Results? "
08/01/2019 - "To systematically review and perform a meta-analysis on the safety and efficacy of endovascular therapy in the treatment of the two most common etiologies of vasculogenic erectile dysfunction (ED): veno-occlusive dysfunction (VOD) and arterial insufficiency (AI). "
03/01/2013 - "Endovascular embolisation therapy for veno-occlusive dysfunction in erectile impotence is a safe and effective therapeutic option with low complication rate and highly technical and clinical success rates."
01/01/2007 - "The diagnosis and treatment of erectile dysfunction has changed dramatically since the availability of safe and effective oral therapies. "
03/01/2007 - "Results are described of a pilot study of the efficacy of sex therapy through the Internet for thirty-nine men with erectile dysfunction or rapid ejaculation. "

06/01/2020 - "Penile prosthesis surgery is currently the most effective treatment for erectile dysfunction when medical treatment is ineffective or contraindicated. "
06/01/2014 - "Device reliability has improved to the point that penile implants are among the most durable mechanical surgical products that contribute to patient and partner satisfaction, which is by far the greatest among all the treatments of erectile dysfunction."
01/01/1997 - "Although penile prostheses are highly effective in the treatment of erectile dysfunction, a small percentage of patients are dissatisfied. "
09/01/1991 - "In view of the alternative treatment options available, the use of alloplastics is now regarded as a last option in the treatment of erectile dysfunction; however, even in 1991 penile implants give the best results known so far."
04/01/1978 - "The inflatable penile prosthesis has improved to be a highly satisfactory method of treating male impotence."

04/01/2009 - "Even 20% of those patients who did not have a nerve preservation got satisfactory erections, Our experience shows that early penile rehabilitation seems to be a good treatment for erectile dysfunction after radical prostatectomy with IPDE5 in fixed doses. "
04/01/1997 - "Nerve-sparing procedures helped reduce the high incidence of impotence that occurs in patients after radical retropubic prostatectomy. "
01/01/2017 - "The pathophysiology of erectile dysfunction post radical prostatectomy is not clearly clarified, and the low efficacy of traditional PDE5i treatment remains a major complaint in contemporary practice. "
11/01/2014 - "Erectile dysfunction (ED) is a major complication after radical prostatectomy (RP); however, debate continues regarding the efficacy of penile rehabilitation in the recovery of the postoperative erectile function (EF). "
01/01/2010 - "Penile injection has been shown to be an effective treatment for erectile dysfunction (ED) following prostatectomy, yet it is not commonly used by these men. "

06/09/2023 - "Herein, a scoping review of clinical trials evaluating the efficacy of low-intensity extracorporeal shockwave therapy in erectile dysfunction to determine the fragility index of trials with clinically significant results. "
01/01/2023 - "The aim of the study was to evaluate whether physical exercise (PE) in addition to extracorporeal shockwave therapy (ESWT) is more effective in improving erectile function as compared to ESWT and PE alone in diabetic patients with erectile dysfunction (ED). "
06/01/2021 - "Low Intensity Extracorporeal Shock Wave Therapy (LI-SWT) has been found to be effective in men with vascular erectile dysfunction (ED) but its efficacy and safety has not been investigated in a predominantly black population so we sought to study this. "
01/01/2023 - "To clarify the efficacy of low-intensity extracorporeal shockwave therapy for patients with erectile dysfunction, compare the efficacy between two types of lithotripters (ED1000 [focused type] and Renova [linear type]), and detect factors indicative of therapeutic gain with the treatment. "
01/01/2018 - "Preliminary results from our study provide further evidence that low-intensity extracorporeal shockwave therapy is a safe and effective treatment modality for erectile dysfunction. "

12/01/1989 - "Recently, intracavernous injections of vasoactive medications have proved beneficial for treating patients with erectile dysfunction. "
01/01/2023 - "To evaluate the safety and efficacy of platelet rich plasma (PRP) injections as a therapeutic modality for mild to moderate erectile dysfunction. "
01/01/1987 - "Their therapeutic value is reduced to the method by self injections, new treatment for impotence, even if it concerns only few impotent patients. "
01/01/2023 - "We assessed the safety and efficacy of 2 injections of platelet-rich plasma for treating mild to moderate erectile dysfunction by conducting a prospective, randomized, double-blind, placebo-controlled clinical trial. "
12/01/2022 - "We conducted a pilot study to evaluate the safety and efficacy of intracavernous PRP injections in patients with vascular erectile dysfunction (ED). "