Conservative Nonhormonal Options for the Treatment of Male Infertility: Antibiotics, Anti-Inflammatory Drugs, and Antioxidants.

Abstract

The nonhormonal medical treatment can be divided into empirical, when the cause has not been identified, and nonempirical, if the pathogenic mechanism causing male infertility can be solved or ameliorated. The empirical nonhormonal medical treatment has been proposed for patients with idiopathic or noncurable oligoasthenoteratozoospermia and for normozoospermic infertile patients. Anti-inflammatory, fibrinolytic, and antioxidant compounds, oligo elements, and vitamin supplementation may be prescribed. Infection, inflammation, and/or increased oxidative stress often require a specific treatment with antibiotics, anti-inflammatory drugs, and/or antioxidants. Combined therapies can contribute to improve sperm quality.

• Authors: Aldo E Calogero, Rosita A Condorelli, Giorgio Ivan Russo, Sandro La Vignera
• Journal: BioMed research international (Biomed Res Int) Vol. 2017 Pg. 4650182 ( 2017) ISSN: 2314-6141 [Electronic] United States
• PMID: 28164122 (Publication Type: Journal Article, Review)

Chemical References

• Anti-Bacterial Agents
• Anti-Inflammatory Agents
• Antioxidants
• Fibrinolytic Agents

Topics

• Anti-Bacterial Agents (pharmacology, therapeutic use)
• Anti-Inflammatory Agents (pharmacology, therapeutic use)
• Antioxidants (pharmacology, therapeutic use)
• Fibrinolytic Agents (pharmacology, therapeutic use)
• Humans
• Infertility, Male (drug therapy)
• Male