Sclerosing Orbital Inflammation Caused by Leishmania braziliensis.

Abstract

Orbital biopsy of nonspecific orbital inflammation, commonly referred to as "orbital pseudotumor," typically shows a combination of polyclonal lymphocytes, plasmocytes, leukocytes, macrophages, and variable degrees of collagen deposition. Herein, we report a patient with a positive history of mucocutaneous leishmaniasis who presented with an orbital mass with a histological profile of idiopathic orbital inflammation. Immunohistochemical and molecular analysis of the orbital specimens demonstrated that the orbital inflammation was associated with the presence of antigens of Leishmania braziliensis and DNA from the parasite.

• Authors: Antonio Augusto V Cruz, Eliza V C Alves-Ferreira, Gherusa Milbratz-Moré, Fernando Chahud, Patricia C Ruy, Maria Irma Seixas Duarte, Angela Kaysel Cruz
• Journal: The American journal of tropical medicine and hygiene (Am J Trop Med Hyg) Vol. 96 Issue 1 Pg. 197-199 (Jan 11 2017) ISSN: 1476-1645 [Electronic] United States
• PMID: 27799649 (Publication Type: Case Reports, Journal Article)
• Copyright: © The American Society of Tropical Medicine and Hygiene.

Topics

• Aged
• Humans
• Leishmania braziliensis (isolation & purification)
• Male
• Orbital Pseudotumor (parasitology, pathology, surgery)