Abstract | OBJECTIVE: METHODS: We measured and compared messenger RNA ( mRNA) levels of ADAMTS13 in peripheral blood cells in patients with systemic lupus erythematosus and healthy control subjects by whole-genome microarray. We retrospectively analyzed the correlations of ADAMTS13 mRNA expression with clinical features, laboratory parameters, therapeutic features, and disease activity (according to the Systemic Lupus Erythematosus Disease Activity Index). We also examined the association of three single nucleotide polymorphisms (rs4962145, rs2285467, and rs685523) of the ADAMTS13 gene with patient characteristics. RESULTS: CONCLUSIONS:
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Authors | Consuelo M López De Padilla, Molly S Hein, Cynthia S Crowson, Christopher S Choo, Abigail B Green, Michelle Petri, Hatice Bilgic, Emily C Baechler, Ann M Reed |
Journal | SAGE open medicine
(SAGE Open Med)
Vol. 1
Pg. 2050312113514404
( 2013)
ISSN: 2050-3121 [Print] England |
PMID | 26770692
(Publication Type: Journal Article)
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