Abstract | OBJECTIVE: METHODS: RESULTS: From the 21 studies that were identified, less than half of the studies found higher acute postoperative pain, higher postoperative analgesic requirements after intraoperative remifentanil use, or both. Coanesthetics to some extent determined this incidence, with mainly studies using volatile agents reporting increased pain levels. There was less evidence when remifentanil was combined with total intravenous anesthesia or a combination of anesthetics. The limited number of studies (n=4) evaluating chronic pain suggested a potential association with the intraoperative use of remifentanil. DISCUSSION:
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Authors | Sjoerd de Hoogd, Sabine J G M Ahlers, Eric P A van Dongen, Ewoudt M W van de Garde, Tanja A T Hamilton-Ter Brake, Albert Dahan, Dick Tibboel, Catherijne A J Knibbe |
Journal | The Clinical journal of pain
(Clin J Pain)
Vol. 32
Issue 8
Pg. 726-35
(08 2016)
ISSN: 1536-5409 [Electronic] United States |
PMID | 26626296
(Publication Type: Journal Article, Review)
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Chemical References |
- Analgesics, Opioid
- Piperidines
- Remifentanil
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Topics |
- Analgesics, Opioid
(administration & dosage)
- Chronic Pain
(epidemiology)
- Humans
- Intraoperative Care
- Pain, Postoperative
(epidemiology)
- Piperidines
(administration & dosage)
- Remifentanil
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