Abstract | OBJECTIVE: METHODS: RESULTS: A 10-year-old girl diagnosed with hereditary tyrosinemia type I and on NTBC treatment presented with photophobia and ocular discomfort in both eyes. An ophthalmologic examination demonstrated bilateral dendritiform epithelial lesions in the central cornea, staining faintly with fluorescein. These lesions were subsequently intermittently treated with topical antivirals for presumed herpes simplex virus keratitis and lubricant eye drops for 9 months without resolution; however, when strict compliance with a protein-restricted diet was instituted, nearly a complete resolution of the lesions was noted at the 4-week follow-up. CONCLUSIONS:
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Authors | Duygu Gulmez Sevim, Koray Gumus, H Dwight Cavanagh |
Journal | Eye & contact lens
(Eye Contact Lens)
Vol. 43
Issue 3
Pg. e7-e9
(May 2017)
ISSN: 1542-233X [Electronic] United States |
PMID | 26322918
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Fluorescent Dyes
- Fluorescein
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Topics |
- Child
- Cornea
(pathology)
- Dendritic Cells
(pathology)
- Diagnosis, Differential
- Eye Infections, Viral
(complications, diagnosis)
- Female
- Fluorescein
(pharmacology)
- Fluorescent Dyes
(pharmacology)
- Humans
- Keratitis, Herpetic
(complications, diagnosis)
- Microscopy, Confocal
- Tyrosinemias
(complications)
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