Allergic bronchopulmonary aspergillosis in an adult with Kartagener syndrome.

Abstract

Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder resulting from immune responses directed against inhaled Aspergillus fumigatus antigens. It manifests with poorly controlled asthma, fleeting pulmonary opacities and structural lung damage in the form of bronchiectasis. Initially defined in individuals suffering from bronchial asthma and cystic fibrosis, it has also been described in patients with other structural lung disorders such as chronic obstructive pulmonary disease, pulmonary tuberculosis, idiopathic bronchiectasis and others. Kartagener syndrome is a manifestation of primary ciliary dyskinesia characterised by the presence of dextrocardia, bronchiectasis and chronic sinusitis. We report a case of ABPA in an adult suffering from Kartagener syndrome. We also performed a systematic review of the literature on the association between Kartagener syndrome and ABPA.

• Authors: Inderpaul Singh Sehgal, Sahajal Dhooria, Amanjit Bal, Ritesh Agarwal
• Journal: BMJ case reports (BMJ Case Rep) Vol. 2015 (Aug 06 2015) ISSN: 1757-790X [Electronic] England
• PMID: 26250371 (Publication Type: Case Reports, Journal Article, Review, Systematic Review)
• Copyright: 2015 BMJ Publishing Group Ltd.

Chemical References

• Antifungal Agents
• Bronchodilator Agents
• Glucocorticoids
• Prednisolone
• Fluticasone
• Formoterol Fumarate

Topics

• Adult
• Antifungal Agents (therapeutic use)
• Aspergillosis, Allergic Bronchopulmonary (complications, diagnostic imaging, drug therapy)
• Bronchodilator Agents (therapeutic use)
• Fluticasone (therapeutic use)
• Formoterol Fumarate (therapeutic use)
• Glucocorticoids (therapeutic use)
• Humans
• Kartagener Syndrome (complications)
• Male
• Prednisolone (therapeutic use)
• Radiography