Pancreatic mucinous cystic neoplasm in a transgender patient.

Abstract

BACKGROUND:

Cystic pancreatic lesions are increasingly more frequent detected clinical entities. Mucinous cystic neoplasm (MCN) is a hormone-related pancreatic tumor (HRTP) with a strong predominance in young and middle-aged females.

CASE PRESENTATION:

Here, we present the case of a 31-year-old surgically transgendered female-to-male patient with a history of alcoholic pancreatitis, on chronic testosterone therapy. He was found to have a pancreatic MCN and underwent distal pancreatectomy and splenectomy.

CONCLUSION:

To our knowledge, this is the first reported case of a transgender patient with a history of hormone replacement therapy (HRT) and pancreatic MCN. We consider possible mechanisms for the pathogenesis to explain this patient's neoplasm.

• Authors: Deshka Foster, Mohammad F Shaikh, Elizabeth Gleeson, Blake D Babcock, Jianping Lin, Robert T Ownbey, Mark E Hysell, Daniel Ringold, Wilbur B Bowne
• Journal: World journal of surgical oncology (World J Surg Oncol) Vol. 13 Pg. 205 (Jun 24 2015) ISSN: 1477-7819 [Electronic] England
• PMID: 26104783 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Cystadenoma, Mucinous (pathology, surgery)
• Female
• Humans
• Male
• Pancreatectomy
• Pancreatic Neoplasms (pathology, surgery)
• Prognosis
• Transgender Persons