Abstract |
Celiac disease (CD) and inflammatory bowel disease (IBD), such as Crohn's disease (CrD) and ulcerative colitis (UC), are chronic inflammatory condition of the gastro-intestinal tract. The prevalence of IBD in celiac patients has been reported as 5-10 times higher than in the general population. The possibility of the presence of CD in IBD should be considered in IBD patients with long-term iron deficiency anemia (IDA) not responsive to iron supplementation. Non-celiac gluten sensitivity (NCGS) is characterized by intestinal and extra intestinal symptoms due to the ingestion of gluten-containing food in subject without CD and/or wheat allergy. Patients with Crohn's disease and SR-NCGS were more significantly affected by joint pains compared to UC patients (50% versus 11.1%). In Crohn's patients, a higher percentage of fatigue (50% versus 38.9%) and headache (27.3% versus 22.2%) was evident. For the association between NCGS and IBD new studies are warranted and, at this moment, a gluten free diet (GFD) may be useful more in CrD than in UC.
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Authors | G Casella, C Di Bella, M Salemme, V Villanacci, E Antonelli, V Baldini, G Bassotti |
Journal | Minerva gastroenterologica e dietologica
(Minerva Gastroenterol Dietol)
Vol. 61
Issue 4
Pg. 267-71
(Dec 2015)
ISSN: 1827-1642 [Electronic] Italy |
PMID | 26006779
(Publication Type: Journal Article, Review)
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Chemical References |
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Topics |
- Celiac Disease
(complications, diagnosis)
- Food Hypersensitivity
(complications, diagnosis)
- Glutens
(adverse effects)
- Humans
- Inflammatory Bowel Diseases
(complications)
- Prevalence
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