The detection of toxigenic Corynebacterium ulcerans from cats with nasal inflammation in Japan.

Abstract

Corynebacterium ulcerans (toxigenic C. ulcerans) produces the diphtheria toxin, which causes pharyngeal and cutaneous diphtheria-like disease in people, and this bacterium is commonly detected in dogs and cats that are reared at home. It is considered dangerous when a carrier animal becomes the source of infection in people. To investigate the carrier situation of toxigenic C. ulcerans of cats bred in Japan, bacteria were isolated from 37 cats with a primary complaint of rhinitis in 16 veterinary hospitals in Osaka. Toxigenic C. ulcerans was detected in two of the cats. By drug sensitivity testing, the detected bacterium was sensitive to all investigated drugs, except clindamycin. It appears necessary to create awareness regarding toxigenic C. ulcerans infection in pet owners because this bacterium is believed to be the causative organism for rhinitis in cats.

• Authors: J Saeki, C Katsukawa, M Matsubayashi, H Nakanishi, M Furuya, H Tani, K Sasai
• Journal: Epidemiology and infection (Epidemiol Infect) Vol. 143 Issue 12 Pg. 2660-5 (Sep 2015) ISSN: 1469-4409 [Electronic] England
• PMID: 25578079 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Bacterial Agents
• Bacterial Toxins

Topics

• Animals
• Anti-Bacterial Agents (pharmacology)
• Bacterial Toxins (genetics, pharmacology)
• Carrier State (microbiology, veterinary)
• Cat Diseases (microbiology)
• Cats
• Cell Survival (drug effects)
• Corynebacterium (drug effects, genetics, isolation & purification)
• Japan
• Male
• Microbial Sensitivity Tests
• Rhinitis (microbiology, veterinary)
• Vero Cells