Abstract | BACKGROUND: METHODS: MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials were searched for relevant controlled trials published in English, from their inception up to May 15th, 2013. Data on low output syndrome, spontaneous return to sinus rhythm, volume of cardioplegia and perioperative myocardial infarction were analyzed. RESULTS: Five studies, totaling 296 patients, were included out of 77 retrieved citations. The microplegia group used less volume of cardioplegia (WMD, -514.79 ml, 95%CI: -705.37 ml to -324.21 ml) when compared with the standard blood cardioplegia group. There were no statistical differences in the incidence of low output syndrome (RR, 0.95, 95%CI: 0.55 to 1.62), spontaneous return to sinus rhythm (RR, 1.64, 95%CI: 0.61 to 4.41) and perioperative myocardial infarction (RR, 0.62, 95%CI: 0.19 to 2.08). CONCLUSIONS: Microplegia was associated with less volume of cardioplegia, whereas the incidence of spontaneous return to sinus rhythm and perioperative myocardial infarction were similar, but large controlled randomized trials are still needed to confirm this.
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Authors | B Gong, B Ji, Y Sun, G Wang, J Liu, Z Zheng |
Journal | Perfusion
(Perfusion)
Vol. 30
Issue 5
Pg. 375-82
(Jul 2015)
ISSN: 1477-111X [Electronic] England |
PMID | 24756305
(Publication Type: Comparative Study, Journal Article, Meta-Analysis, Review, Systematic Review)
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Copyright | © The Author(s) 2014. |
Topics |
- Clinical Trials as Topic
- Heart Arrest, Induced
(adverse effects, methods)
- Hemodilution
(adverse effects)
- Humans
- Myocardial Infarction
(physiopathology, surgery)
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