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Coronary Artery Bypass (Coronary Artery Bypass Surgery)

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Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.

Also Known As:

Coronary Artery Bypass Surgery; Aortocoronary Bypass; Bypass Surgery, Coronary Artery; Coronary Artery Bypass Grafting; Aortocoronary Bypasses; Artery Bypass, Coronary; Artery Bypasses, Coronary; Bypass, Aortocoronary; Bypasses, Aortocoronary; Bypasses, Coronary Artery; Coronary Artery Bypasses; Bypass, Coronary Artery

Networked: 12286 relevant articles (428 outcomes, 1489 trials/studies)

Relationship Network

Therapy Context: Research Results

Operative Surgical Procedures: 8
- Thoracic Surgical Procedures: 64
  - Cardiac Surgical Procedures: 275
    - Myocardial Revascularization: 1346
      - Coronary Artery Bypass: 12286
        Off-Pump Coronary Artery Bypass: 711
        Internal Mammary-Coronary Artery Anastomosis
- Cardiovascular Surgical Procedures: 25
  - Cardiac Surgical Procedures: 275
    - Myocardial Revascularization: 1346
      - Coronary Artery Bypass: 12286
        Off-Pump Coronary Artery Bypass: 711
        Internal Mammary-Coronary Artery Anastomosis
  - Vascular Surgical Procedures: 73
    - Vascular Grafting: 40
      - Coronary Artery Bypass: 12286
        Off-Pump Coronary Artery Bypass: 711
        Internal Mammary-Coronary Artery Anastomosis

Experts

1.	Serruys, Patrick W: 47 articles (11/2015 - 02/2003)
2.	Peterson, Eric D: 46 articles (06/2015 - 08/2002)
3.	Stone, Gregg W: 45 articles (01/2016 - 08/2003)
4.	Holmes, David R: 41 articles (04/2015 - 05/2002)
5.	Mehran, Roxana: 39 articles (01/2016 - 08/2003)
6.	Puskas, John D: 34 articles (09/2015 - 01/2003)
7.	Mack, Michael J: 33 articles (12/2015 - 01/2004)
8.	Guyton, Robert A: 33 articles (09/2015 - 01/2003)
9.	Harrington, Robert A: 32 articles (05/2015 - 01/2002)
10.	Smith, Peter K: 32 articles (05/2015 - 01/2002)

Related Diseases

1.	Coronary Artery Disease (Coronary Atherosclerosis) 01/01/2014 - "Coronary artery bypass graft (CABG) surgery is one of the most effective treatments for coronary artery disease. " 02/01/1999 - "In most patients with diabetes who have multivessel coronary artery disease, coronary artery bypass grafting is superior to coronary angioplasty for improving long-term cardiovascular prognosis. " 10/01/1998 - "This study confirms the excellent clinical results of coronary artery bypass grafting (CABG) in patients with coronary artery disease and LV dysfunction; improvement in LV function can be documented objectively and is correlated with reperfusion of hibernating myocardium. " 02/01/1991 - "The better myocardial protection, more complete revascularization, and improved graft patency rates that have occurred in the last decade imply that survival following coronary artery bypass may be improved in a broader spectrum of coronary artery disease patients than documented in the randomized trials. " 06/01/2013 - "In patients with chronic coronary artery disease different therapeutic strategies, such as optimal medical therapy, revascularization by percutaneous coronary intervention or coronary artery bypass grafting have been shown to improve the prognosis and symptoms and yield proven superiority over other treatment strategies in different patient populations. "
2.	Myocardial Infarction 01/01/2015 - "Many studies have unequivocally demonstrated that coronary artery bypass grafting surgery generally leads to significant reduction in heart rate variability, which is even more pronounced than after myocardial infarction. " 09/10/2013 - "The prevalence of myocardial infarction history, percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) history in male group were significantly greater than that in female group (48.0% vs 39.9%, P < 0.05; 30.6% vs 22.3%, P < 0.05; 19.9% vs 10.3%, P < 0.01). " 07/01/2010 - "Successful recanalization was associated with a significant reduction in subsequent coronary artery bypass graft surgery (CABG) (OR 0.22, 95% CI 0.17-0.27) but not in myocardial infarction (OR 0.74, 95% CI 0.44-1.25) or major adverse cardiac events (OR 0.81, 95% CI 0.55-1.21). " 04/01/2006 - "In patients with previous myocardial infarction, treatment with skeletal myoblasts in conjunction with coronary artery bypass is safe and feasible and is associated with an increased global and regional left ventricular function, improvement in viability, and perfusion of cardiac tissue and no significant incidence of arrhythmias." 03/01/2004 - "HRQoL improved significantly in patients after coronary artery bypass grafting (CABG) but not in patients after myocardial infarction. "
3.	Atrial Fibrillation 01/01/2002 - "beta-adrenoceptor antagonists (b-blockers) are very effective in preventing atrial fibrillation after coronary artery bypass surgery. " 01/01/2009 - "In the subgroup of patients with coronary artery bypass graft with our without simultaneous valve surgery (n=312), Auricall monitoring resulted in a significantly reduced incidence of atrial fibrillation (14% vs 26%, p=0.016). " 01/01/2004 - "Nonsteroidal anti-inflammatory medications were relatively safe and effective in significantly reducing the incidence of atrial fibrillation after coronary artery bypass graft surgery." 01/01/2013 - "Prevention of post-coronary artery bypass grafting (CABG) atrial fibrillation: efficacy of prophylactic beta-blockers in the modern era: a meta-analysis of latest randomized controlled trials." 01/01/2012 - "Meta-analysis of randomized controlled trials on the efficacy of thoracic epidural anesthesia in preventing atrial fibrillation after coronary artery bypass grafting."
4.	Stroke (Strokes) 08/01/2006 - "Despite major improvement in surgical techniques and intensive care management, stroke remains one of the most devastating complications of coronary artery bypass grafting (CABG). " 02/01/1997 - "Significantly reduced incidence of stroke during coronary artery bypass grafting using transesophageal echocardiography." 02/01/2004 - "Despite the fact that this is a meta-analysis of observational studies and adjustment for differences in baseline risk factors between OPCAB and CPB patients was not possible, we believe that this study suggests that the OPCAB technique might be associated with reduced incidence of stroke in the elderly patients undergoing coronary artery bypass grafting." 05/01/1999 - "This study was designed to evaluate the efficacy of a protocol of systematic screening of the ascending aorta and internal carotid arteries and individualization of the surgical strategy to the ascending aorta and internal carotid arteries status in reducing the stroke incidence among patients undergoing coronary artery bypass grafting. " 04/01/2009 - "Efficacy of intraoperative epiaortic ultrasound scanning for preventing stroke after coronary artery bypass surgery."
5.	Myocardial Ischemia (Ischemic Heart Diseases) 03/01/2002 - "A major effect of coronary artery bypass grafting (CABG) in patients with ischemic heart disease and impaired left ventricular (LV) contractile function is believed to be an improvement in LV function due to recovery of dysfunctional, but viable myocardium. " 08/01/1996 - "The sequential coronary artery bypass grafting with the left internal thoracic artery was effective for infantile ischemic heart disease." 11/01/2006 - "The cardiopulmonary bypass (CPB) has allowed the establishment of coronary artery bypass graft surgery (CABG) to be a safe and effective treatment for patients with ischemic heart disease. " 10/13/2009 - "The aim of the present study was to identify predictors of postoperative improvement in moderate IMR in patients with ischemic heart disease undergoing elective isolated coronary artery bypass graft surgery. " 08/01/2013 - "The efficacy of coronary artery bypass graft (CABG) surgery for patients with ischemic heart disease is dependent on the patency of the selected conduit. "

Related Drugs and Biologics

1.	glucuronyl glucosamine glycan sulfate (Vessel)
2.	Magnesium
3.	clopidogrel (Plavix)
4.	Aspirin (Acetylsalicylic Acid)
5.	Tranexamic Acid (AMCA)
6.	Nicardipine (Dagan)
7.	Amiodarone (Amiodarona)
8.	Aprotinin (Trasylol)
9.	Ticagrelor
10.	prasugrel

Related Therapies and Procedures

1.	Transplants (Transplant)
2.	Angioplasty (Angioplasty, Transluminal)
3.	Drug-Eluting Stents
4.	Coronary Balloon Angioplasty (Percutaneous Transluminal Coronary Angioplasty)
5.	Cardiopulmonary Bypass (Heart-Lung Bypass)