Abstract | BACKGROUND: METHODS: A hospital based cross sectional study was conducted on 200 hypertensive patients on treatment in southwest Ethiopia. A pretested structured questionnaire was used to collect data from participants and their clinical records. Blood pressure and anthropometric measurements were taken according to recommended standards. Left ventricular mass was measured by transthoracic echocardiography. Associations between categorical variables were assessed using chi-square test and odds ratio with 95% confidence interval. Logistic regression model was done to identify risks factors of LVH. P values of < 0.05 were considered as statistically significant. RESULTS: The mean age, systolic blood pressure, diastolic blood pressure and body mass index were 55.7 ± 11.3 years, 139.2 ± 7.7 mmHg, 89.2 ± 5.7 mmHg and 24.2 ± 3.4 Kg/m2 respectively. The overall prevalence of LVH among these study subjects was 52%. Age ≥50 years (OR: 3.49, 95% CI 1.33-9.14, P = 0.011), female gender (OR: 7.69, 95% CI 3.23-20.0, P < 0.001), systolic blood pressure ≥140 mmHg (OR: 2.85, 95% CI 1.27-6.41, P = 0.011), and duration of hypertension (OR: 3.59, 95% CI 1.47-8.76, P = 0.005) were independent predictors of left ventricular hypertrophy. Angiotensin converting enzyme ( ACE) inhibitors were the only antihypertensive drugs associated with lower risk of left ventricular hypertrophy (OR: 0.08, 95% CI 0.03-0.19, p < 0.001). CONCLUSIONS:
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Authors | Gari Negeri Jaleta, Esayas Kebede Gudina, Wondim Getinet |
Journal | BMC research notes
(BMC Res Notes)
Vol. 7
Pg. 45
(Jan 20 2014)
ISSN: 1756-0500 [Electronic] England |
PMID | 24444396
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Angiotensin-Converting Enzyme Inhibitors
- Antihypertensive Agents
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Topics |
- Adult
- Age Factors
- Aged
- Angiotensin-Converting Enzyme Inhibitors
(therapeutic use)
- Antihypertensive Agents
(therapeutic use)
- Black People
- Body Mass Index
- Comorbidity
- Cross-Sectional Studies
- Diabetes Mellitus, Type 2
(epidemiology)
- Ethiopia
(epidemiology)
- Female
- Humans
- Hypertension
(drug therapy, epidemiology)
- Hypertrophy, Left Ventricular
(diagnostic imaging, epidemiology)
- Male
- Middle Aged
- Obesity
(epidemiology)
- Prevalence
- Risk Factors
- Sex Factors
- Surveys and Questionnaires
- Ultrasonography
- Young Adult
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