Abstract | AIM: METHODS: RESULTS: Blood lipids, oxysterols and vitamin E were not affected by either thermal or tap water consumption. Fasting gallbladder volume was significantly (P < 0.005) smaller at the end of the study than at baseline in the TW (15.7 ± 1.1 mL vs 20.1 ± 1.7 mL) but not in the tap water group (19.0 ± 1.4 mL vs 19.4 ± 1.5 mL). Total serum BA concentration was significantly (P < 0.05) higher at the end of the study than at baseline in the TW (5.83 ± 1.24 μmol vs 4.25 ± 1.00 μmol) but not in the tap water group (3.41 ± 0.46 μmol vs 2.91 ± 0.56 μmol). The increased BA concentration after TW consumption was mainly accounted for by glycochenodeoxycholic acid. The number of pasta (P < 0.001), meat (P < 0.001) and vegetable (P < 0.005) portions consumed during the study and of bowel movements per day (P < 0.05) were significantly higher in the TW than in the tap water group. Body weight did not change at the end of the study as compared to baseline in both groups. CONCLUSION: Sulphate- bicarbonate- calcium water consumption has a positive effect on lithogenic risk and intestinal transit and allows maintenance of a stable body weight despite a high food intake.
|
Authors | Stefano Ginanni Corradini, Flaminia Ferri, Michela Mordenti, Luigi Iuliano, Maria Siciliano, Maria Antonella Burza, Bruno Sordi, Barbara Caciotti, Maria Pacini, Edoardo Poli, Adriano De Santis, Aldo Roda, Carolina Colliva, Patrizia Simoni, Adolfo Francesco Attili |
Journal | World journal of gastroenterology
(World J Gastroenterol)
Vol. 18
Issue 9
Pg. 930-7
(Mar 07 2012)
ISSN: 2219-2840 [Electronic] United States |
PMID | 22408352
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Bicarbonates
- Bile Acids and Salts
- Sulfates
- Triglycerides
- Water
- Vitamin E
- Cholesterol
- Calcium
|
Topics |
- Aged
- Atherosclerosis
(prevention & control)
- Bicarbonates
(chemistry, pharmacology, therapeutic use)
- Bile Acids and Salts
(blood)
- Body Weight
(drug effects)
- Calcium
(chemistry, pharmacology, therapeutic use)
- Cholesterol
(blood)
- Constipation
(drug therapy)
- Dyspepsia
(drug therapy)
- Eating
(drug effects)
- Female
- Gallbladder
(anatomy & histology, drug effects)
- Gallstones
(prevention & control)
- Humans
- Middle Aged
- Postmenopause
- Risk Factors
- Sulfates
(chemistry, pharmacology, therapeutic use)
- Triglycerides
(blood)
- Vitamin E
(blood)
- Water
(chemistry, pharmacology)
|