Abstract | BACKGROUND: METHODS: RESULTS: A highly significant correlation was noted between simultaneous ABG PCO(2) samplings and TcPCO(2) measured (R = 0.85, p < 0.001). Mean baseline TcPCO(2) level was 41.7 ± 10.3 mm Hg (±SD) (range 35-66 mmHg)], and peak measurement during the procedure was 61 ± 17.1 mm Hg (range 41-111 mmHg). The mean increase in TcPCO(2) during bronchoscopy was 19.2 (range 3.7-45 mmHg) [p < 0.0001]. Mean duration of significant hypercapnea (TcPCO(2) > 55 mmHg), observed in 7 (46%) patients, was 9 min (range 0-53). CONCLUSIONS: Bronchoscopy performed under conscious sedation in patients with severe COPD is frequently associated with significant hypoventilation that can only be detected by TcPCO(2) monitoring. Combined measurement of SpO(2) and TcPCO(2) during bronchoscopy enhances patient safety, helps guide administration of sedation, and can alert physicians to the need for anesthesia reversal following completion of bronchoscopic interventions.
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Authors | Oren Fruchter, Uri Carmi, Edward P Ingenito, Yeal Refaeli, Mordechai R Kramer |
Journal | Respiratory medicine
(Respir Med)
Vol. 105
Issue 4
Pg. 602-7
(Apr 2011)
ISSN: 1532-3064 [Electronic] England |
PMID | 21115237
(Publication Type: Journal Article, Validation Study)
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Copyright | Copyright © 2010 Elsevier Ltd. All rights reserved. |
Chemical References |
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Topics |
- Adult
- Aged
- Blood Gas Monitoring, Transcutaneous
- Bronchoscopy
(adverse effects, methods)
- Carbon Dioxide
(blood)
- Conscious Sedation
(adverse effects, methods)
- Female
- Humans
- Hypoventilation
(diagnosis, etiology, physiopathology)
- Male
- Middle Aged
- Monitoring, Intraoperative
- Pulmonary Disease, Chronic Obstructive
(complications, physiopathology, surgery)
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