17-year-old girl with headache and complex partial seizure.

Abstract

Supratentorial cortical ependymoma is a rare clinical entity where ependymoma occurring in the cortex without any connection to the ventricular system since ependymoma usually arises from the lining of the ventricular system or central canal of spinal cord. There have been 14 such cases reported in the literature.We report the first case of a supratentorial extraaxial cortical anaplastic ependymoma with minimal cortical attachment in a 17-years-old girl, presented with headache and complex partial seizure. Histological features of anaplasia including numerous mitoses, necrosis and high Ki-67 lead to postoperative adjuvant radiation therapy although gross total resection was achieved.

• Authors: Eun Kyung Park, Yun-Ho Lee, Dong-Seok Kim, Joong-Un Choi, Tae-Seung Kim, Kyu-Won Shim
• Journal: Brain pathology (Zurich, Switzerland) (Brain Pathol) Vol. 20 Issue 6 Pg. 1111-4 (Nov 2010) ISSN: 1750-3639 [Electronic] Switzerland
• PMID: 20925697 (Publication Type: Case Reports, Journal Article)

Chemical References

• 12E7 Antigen
• Antigens, CD
• CD99 protein, human
• Cell Adhesion Molecules
• Glial Fibrillary Acidic Protein
• Ki-67 Antigen

Topics

• 12E7 Antigen
• Adolescent
• Antigens, CD (metabolism)
• Cell Adhesion Molecules (metabolism)
• Craniotomy
• Epilepsy, Complex Partial (complications, surgery)
• Female
• Glial Fibrillary Acidic Protein (metabolism)
• Headache (complications, surgery)
• Humans
• Ki-67 Antigen (metabolism)