Three-year follow-up of a girl with chronic paroxysmal hemicrania.

Abstract

This is a follow-up report of a girl, 5 years 4 months old, with classic symptoms of chronic paroxysmal hemicrania from the age of 2 years 3 months who had a complete response to indomethacin therapy. The patient suffered from frequent episodes of severe unilateral headaches for 1 year and 10 months before the diagnosis of chronic paroxysmal hemicrania was established. Indomethacin treatment lasted for 2 years and 6 months. During the first year of treatment, several doses of indomethacin were missed, which was followed by immediate return of hemicrania episodes and then quick resolution of symptoms after administration of indomethacin. After 2 years and 6 months of treatment, the parents missed the treatment for 1 week and the episodes did not recur. The treatment was discontinued. The patient was free from pain and off the medication 1 year later.

• Authors: Inga Talvik, Aleksandr Peet, Tiina Talvik
• Journal: Pediatric neurology (Pediatr Neurol) Vol. 40 Issue 1 Pg. 68-9 (Jan 2009) ISSN: 0887-8994 [Print] United States
• PMID: 19068259 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal
• Indomethacin

Topics

• Anti-Inflammatory Agents, Non-Steroidal (administration & dosage, therapeutic use)
• Child, Preschool
• Diagnosis, Differential
• Female
• Follow-Up Studies
• Headache (drug therapy, physiopathology)
• Humans
• Indomethacin (administration & dosage, therapeutic use)
• Paroxysmal Hemicrania (diagnosis, drug therapy, physiopathology)
• Treatment Outcome