Abstract | OBJECTIVE: METHODS: A prospective, double-blind trial of 375 non-elective cesarean-section cases was carried out. Study antibiotics (2 g) were administered intravenously (IV) at cord clamping only. RESULTS: Demographic and clinical variables between the 2 study groups were similar. No significant differences were noted in major or minor morbidity or in infectious morbidities for patients receiving the 2 prophylactic regimens. The occurrence of postoperative endometritis was likewise similar for the subjects receiving cefoxitin (10%) and cefotetan (15%). When cases whose surgery lasted >60 min were evaluated separately, no differences in outcomes between the 2 groups were identified. CONCLUSIONS: These findings confirm our hypothesis that the half-life difference between these 2 agents does not impact on single-dose Prophylactic efficacy in cesarean section.
|
Authors | B Gonik, J McGregor |
Journal | Infectious diseases in obstetrics and gynecology
(Infect Dis Obstet Gynecol)
Vol. 2
Issue 3
Pg. 120-5
( 1994)
ISSN: 1064-7449 [Print] Egypt |
PMID | 18475377
(Publication Type: Journal Article)
|