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Endometritis

Inflammation of the ENDOMETRIUM, usually caused by intrauterine infections. Endometritis is the most common cause of postpartum fever.
Also Known As:
Endomyometritis
Networked: 1056 relevant articles (96 outcomes, 139 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Infection
2. Wound Infection (Wound Infections)
3. Sepsis (Septicemia)
4. Chorioamnionitis
5. Inflammation

Experts

1. Heuwieser, W: 14 articles (01/2014 - 03/2000)
2. Caritis, Steve N: 8 articles (10/2015 - 12/2004)
3. Varner, Michael W: 8 articles (10/2015 - 12/2004)
4. Gilbert, R O: 8 articles (06/2015 - 09/2009)
5. Galvão, K N: 8 articles (09/2014 - 04/2009)
6. Spong, Catherine Y: 8 articles (04/2012 - 12/2004)
7. Leveno, Kenneth J: 7 articles (10/2015 - 12/2004)
8. Sorokin, Yoram: 7 articles (10/2015 - 12/2004)
9. Wapner, Ronald J: 7 articles (10/2015 - 12/2004)
10. Drillich, M: 7 articles (01/2014 - 09/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Endometritis:
1. Anti-Bacterial Agents (Antibiotics)IBA
01/01/2014 - "Whereas the previous version of this review showed a statistically significant reduction in endometritis with the use of antibiotics, no such effect was shown in this update (average risk ratio (RR) 0.34, 95% confidence interval (CI) 0.05 to 2.31). "
03/01/1984 - "On the other hand, the presence of a mixture of high- and low-virulence organisms in the AMC or of high-virulence anaerobes only--more specifically, gram-negative anaerobes--was predictive of subsequent postcesarean endometritis only for patients who did not receive perioperative antibiotics, and therapy significantly decreased the incidence of endometritis associated with these AMC patterns. "
11/01/1983 - "There was a significant reduction in the incidence of postoperative endomyometritis in the group prophylactic antibiotics (12/45, 26.7%) compared to the control group not given prophylactic antibiotics (20/39, 51.3%), p less than 0.05. "
01/01/1986 - "Administration of antibiotics by irrigation is equally effective in preventing postoperative febrile morbidity and endomyometritis as intravenous dosing and a combination of intravenous and irrigation. "
11/01/1983 - "Other identified advantages that resulted from the use of prophylactic antibiotics included a shorter duration of treatment required for postoperative endomyometritis in the group given prophylactic antibiotics and an increased likelihood of being cured by initial therapy for endomyometritis in the group given prophylactic antibiotics (100% versus 70%). "
2. Gentamicins (Gentamicin)FDA LinkGeneric
3. Clindamycin (Cleocin)FDA LinkGeneric
4. Ampicillin (Omnipen)FDA LinkGeneric
5. Cefoxitin (Cefoxitin Sodium)FDA LinkGeneric
6. Ticarcillin (Tarcil)FDA Link
7. DinoprostIBA
8. Metronidazole (Metric)FDA LinkGeneric
9. sultamicillin (ampicillin-sulbactam)FDA LinkGeneric
10. Prostaglandins F (PGF)IBA

Therapies and Procedures

1. Cesarean Section (Caesarean Section)
12/01/1980 - "Patients who underwent primary cesarean section were at significantly greater risk of developing postoperative endometritis than were patients undergoing a repeat procedure. "
05/01/1980 - "Therefore, patients with post-cesarean section endomyometritis have less febrile morbidity if they are initially treated with a drug effective against anaerobic bacteria, especially B fragilis."
07/01/1991 - "A retrospective analysis of 1000 case histories of women who delivered by cesarean section has helped define the principal factors of postsurgical endometritis risk. "
01/01/2012 - "The use of amnioinfusion for potential or suspected umbilical cord compression may be of considerable benefit to mother and baby by reducing the occurrence of variable FHR decelerations, improving short-term measures of neonatal outcome, reducing maternal postpartum endometritis and lowering the use of caesarean section, although there were methodological limitations to the trials reviewed here. "
01/01/2012 - "Transcervical amnioinfusion for potential or suspected umbilical cord compression was associated with the following reductions: caesarean section overall (13 trials, 1493 participants; average risk ratio (RR) 0.62, 95% confidence interval (CI) 0.46 to 0.83); fetal heart rate (FHR) decelerations (seven trials, 1006 participants; average RR 0.53, 95% CI 0.38 to 0.74); Apgar score less than seven at five minutes (12 trials, 1804 participants; average RR 0.47, 95% CI 0.30 to 0.72); meconium below the vocal cords (three trials, 674 participants, RR 0.53, 95% CI 0.31 to 0.92); postpartum endometritis (six trials, 767 participants; RR 0.45, 95% CI 0.25 to 0.81) and maternal hospital stay greater than three days (four trials, 1051 participants; average RR 0.45, 95% CI 0.25 to 0.78). "
2. Antibiotic Prophylaxis
3. Neonatal Intensive Care
4. Curettage
5. Aftercare (After-Treatment)