This study was designed to clarify the efficacy of combination of
thyroid hormone (
euthyrox)
therapy and percutaneous
ethanol injection (PEI) in benign nodular
thyroid diseases. 55 patients with benign
nodular goiter after the first PEI session during the whole study period (from 3 till 12 months after PEI) daily received
euthyrox in a dosage - 50 mkg. 48 women and 7 men with
thyroid nodules of the various sizes, structures and echogenecity have been included in the study group. The control group consisted of 32 patients: 29 women and 3 men in the same age range as in the study group. In both groups PEI procedure was performed but in the control group no
thyroid hormone was added. In patients who were receiving 50 mkg daily after 3 months of PEI progressive reduction of the nodule sizes was registered, the volume of a thyroid gland has decreased and approached to normal parameters (15,79+/-1,21 ml), and in 6-2 months the normal volume of the thyroid gland was registered. Thus, combination of
thyroid hormone therapy and percutaneous
ethanol injection (PEI) in treatment of patients with benign
nodular goiter normalizes the size of a thyroid gland.
Euthyrox is the additional factor causing reduction of
thyroid nodules and constraining occurrence of new nodules in a thyroid gland.