Abstract | AIM: METHODS: Patients with ulcerative colitis and FAP syndrome were stratified into groups with pouches after surgery, pouches without or with pouchitis. Biopsies from terminal ileum from a healthy intestine or from normal terminal ileum of patients with ulcerative colitis served as controls. mRNA from pouches and controls was analysed for defensin and cytokine expression. RESULTS: CONCLUSION:
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Authors | Karlheinz Kiehne, Gabriele Brunke, Franziska Wegner, Tomas Banasiewicz, Ulrich R Folsch, Karl-Heinz Herzig |
Journal | World journal of gastroenterology
(World J Gastroenterol)
Vol. 12
Issue 7
Pg. 1056-62
(Feb 21 2006)
ISSN: 1007-9327 [Print] United States |
PMID | 16534846
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Cytokines
- Defensins
- RNA, Messenger
- alpha-Defensins
- beta-Defensins
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Topics |
- Adenomatous Polyposis Coli
(genetics, metabolism, pathology)
- Adolescent
- Adult
- Chronic Disease
- Colitis, Ulcerative
(genetics, metabolism, pathology)
- Colonic Pouches
(pathology)
- Cytokines
(biosynthesis, genetics)
- Defensins
(biosynthesis, genetics)
- Female
- Gene Expression Regulation
- Homeostasis
- Humans
- Ileum
(cytology, metabolism, pathology)
- Immune System
(physiology)
- Intestinal Mucosa
(cytology, metabolism, pathology)
- Male
- Middle Aged
- Pouchitis
(genetics, metabolism, pathology)
- Proctocolectomy, Restorative
- RNA, Messenger
(genetics, metabolism)
- alpha-Defensins
(biosynthesis, genetics)
- beta-Defensins
(biosynthesis, genetics)
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