[Histochemical light and electron microscopic investigations on an eosinophilic granuloma].

Abstract

An eosinophilic granuloma has been investigated by means of histochemical proofs for enzymes and tissue elements and common staining methods. The best method was be found the proof for the enzyme phenol oxidase (EC 1.14.18.1). In this way it is possible to determine eosinophils rapidly and surely and to receive an overview on the frequency and distribution of these cells. The histiocytic-like cells was identified electron microscopical as Langerhans' cells. This cells are in narrow contact to many eosinophilic granulocytes. Their granula have manifold changes in their structure. The granula are possibly able to produce new structures of the cell. The eosinophilic granuloma correspond to a cell mediating immunological defence reaction approximate to the type of a delayed hypersensitivity.

• Authors: H Schmidt, R Krell, D Krell
• Journal: Acta histochemica (Acta Histochem) Vol. 92 Issue 2 Pg. 113-26 ( 1992) ISSN: 0065-1281 [Print] Germany
• Vernacular Title: Histochemische licht- und elektronenmikroskopische Untersuchungen am eosinophilen Granulom.
• PMID: 1642101 (Publication Type: English Abstract, Journal Article)

Chemical References

• Monophenol Monooxygenase
• Esterases
• Alkaline Phosphatase
• Acid Phosphatase

Topics

• Acid Phosphatase (analysis)
• Alkaline Phosphatase (analysis)
• Eosinophils (enzymology, pathology, ultrastructure)
• Esterases (analysis)
• Granuloma (pathology)
• Histocytochemistry
• Humans
• Langerhans Cells (pathology, ultrastructure)
• Microscopy, Electron
• Monophenol Monooxygenase (analysis)
• Skin Diseases (pathology)