Recurrent bilateral mammary fibromatosis (desmoid tumor) imaged with technetium-99m pentavalent dimercaptosuccinic acid [99mTc-(V)DMSA] scintimammography.

Abstract

BACKGROUND:

Breast fibromatosis is a rare, benign, recurring, locally destructive entity.

CASE:

A 35-year-old woman underwent right-sided lumpectomy, revealing fibromatosis with epithelial hyperplasia. Two years later, she was re-evaluated due to a three times as large mass recurrence on X-ray mammography. (99m)Tc-(V)DMSA scintimammography revealed diffuse increased radiotracer uptake occupying the entire breast. A less widespread similar uptake was observed in the contralateral breast. Mammography did identify neither the posterior margins of the mass nor the left-sided lesion. The patient underwent mastectomy and left-sided open biopsy, revealing bilateral fibromatosis. Ki-67 expression was moderate.

CONCLUSIONS:

(99m)Tc-(V)DMSA scintimammography can provide information regarding the nature of the lesion, its extent and bilateral involvement (especially in dense breasts) and could prove useful as a predictor of its potential for recurrence.

• Authors: Vassilios Papantoniou, John Koutsikos, Maria Sotiropoulou, Eleni Feida, Spyridon Tsiouris
• Journal: Gynecologic oncology (Gynecol Oncol) Vol. 97 Issue 3 Pg. 964-9 (Jun 2005) ISSN: 0090-8258 [Print] United States
• PMID: 15896828 (Publication Type: Case Reports, Journal Article)

Chemical References

• Radiopharmaceuticals
• Technetium Tc 99m Dimercaptosuccinic Acid
• Technetium

Topics

• Adult
• Breast Neoplasms (diagnostic imaging)
• Female
• Fibromatosis, Aggressive (diagnostic imaging)
• Humans
• Mammography (methods)
• Neoplasm Recurrence, Local (diagnostic imaging)
• Radionuclide Imaging
• Radiopharmaceuticals
• Technetium
• Technetium Tc 99m Dimercaptosuccinic Acid