Abstract | BACKGROUND: METHODS: RESULTS: FH subjects with coronary ectasia had significantly higher fasting plasma insulin levels than those without (12.6+/-1.4 vs. 7.7+/-0.5 mU/l; p<0.05). Also, plasma insulin levels during oral glucose tolerance test tended to be higher in the former than in the latter. CONCLUSIONS: Plasma insulin level could be an important determinant of the development of coronary artery ectasia in Japanese heterozygous FH men.
|
Authors | Yuko Murase, Kunimasa Yagi, Junji Kobayashi, Atsushi Nohara, Akimichi Asano, Junji Koizumi, Hiroshi Mabuchi |
Journal | Clinica chimica acta; international journal of clinical chemistry
(Clin Chim Acta)
Vol. 355
Issue 1-2
Pg. 33-9
(May 2005)
ISSN: 0009-8981 [Print] Netherlands |
PMID | 15820475
(Publication Type: Journal Article)
|
Chemical References |
|
Topics |
- Adult
- Asian People
- Coronary Stenosis
(blood, etiology)
- Glucose Tolerance Test
- Heterozygote
- Humans
- Hyperinsulinism
(complications)
- Hyperlipoproteinemia Type II
(complications, genetics)
- Male
- Middle Aged
- Mutation
- Receptors, LDL
(genetics)
|