Abstract | OBJECTIVE: To determine the incidence, risk factors, and outcome of barotrauma in a cohort of mechanically ventilated patients where limited tidal volumes and airway pressures were used. DESIGN AND SETTING: Prospective cohort of 361 intensive care units from 20 countries. PATIENTS AND PARTICIPANTS: A total of 5183 patients mechanically ventilated for more than 12 h. MEASUREMENTS AND RESULTS: CONCLUSIONS: In a cohort of patients in whom airway pressures and tidal volume are limited, barotrauma is more likely in patients ventilated due to underlying lung disease (acute or chronic). Barotrauma was also associated with a significant increase in the ICU length of stay and mortality.
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Authors | Antonio Anzueto, Fernando Frutos-Vivar, Andres Esteban, Inmaculada Alía, Laurent Brochard, Thomas Stewart, Salvador Benito, Martin J Tobin, Jose Elizalde, Fernando Palizas, Cide M David, Jorge Pimentel, Marco González, Luis Soto, Gabriel D'Empaire, Paolo Pelosi |
Journal | Intensive care medicine
(Intensive Care Med)
Vol. 30
Issue 4
Pg. 612-9
(Apr 2004)
ISSN: 0342-4642 [Print] United States |
PMID | 14991090
(Publication Type: Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't)
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Topics |
- Adult
- Aged
- Asthma
(pathology, therapy)
- Barotrauma
(etiology, mortality, therapy)
- Cohort Studies
- Female
- Humans
- Incidence
- Intensive Care Units
- Lung
(pathology)
- Male
- Middle Aged
- Prognosis
- Prospective Studies
- Pulmonary Disease, Chronic Obstructive
(pathology, therapy)
- Respiration, Artificial
(adverse effects)
- Respiratory Distress Syndrome
(pathology, therapy)
- Risk Factors
- Survival Rate
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