[Improvement of tardive dyskinesia after treatment with olanzapine].

Abstract

Tardive dyskinesia is a severe complication of neuroleptic treatment. It may develop weeks, even years after starting a neuroleptic treatment and the symptoms may be irreversible. Neuroleptic compounds are not only used in cases of schizophrenia, but also in cases of severe depression with delusional symptoms. We want to present the case of a 67 year old female patient who developed haloperidol induced dyskinesea and stress unto the successful treatment of this complication with olanzapine in combination with paroxetine. Under this regime not only the improvement of the depression, but also of the tardive dyskinesea was impressive.

• Authors: Steve Truöl, Christoph Von Hippel, Jan Raape, Frank König
• Journal: Psychiatrische Praxis (Psychiatr Prax) Vol. 29 Issue 6 Pg. 315-7 (Sep 2002) ISSN: 0303-4259 [Print] Germany
• Vernacular Title: Besserung tardiver Dyskinesien unter Therapie mit Olanzapin.
• PMID: 12224042 (Publication Type: Case Reports, Journal Article)

Chemical References

• Benzodiazepines
• Pirenzepine
• Paroxetine
• Haloperidol
• Olanzapine

Topics

• Affective Disorders, Psychotic (diagnosis, drug therapy, psychology)
• Aged
• Benzodiazepines
• Depressive Disorder, Major (diagnosis, drug therapy, psychology)
• Drug Therapy, Combination
• Dyskinesia, Drug-Induced (diagnosis, drug therapy)
• Female
• Haloperidol (adverse effects, therapeutic use)
• Humans
• Neurologic Examination (drug effects)
• Olanzapine
• Paroxetine (adverse effects, therapeutic use)
• Patient Admission
• Pirenzepine (adverse effects, analogs & derivatives, therapeutic use)