[Circadian monitoring of intragastric pH in evaluation of efficiency of antisecretory therapy of duodenal ulcer].

Abstract

Inhibitors of proton pump are thought "golden standard" in the treatment of ulcer. Usage of omeprasol generics in standard doses sometimes fail to adequately reduce acid production. In pain persistence in patients with duodenal ulcer receiving standard antisecretory therapy it is effective to control it with 24-h intragastric pH-metry which either indicate the necessity of dose correction or another cause of pain (concomitant affections as a rule). As shown by 24-h pH-metry, a new generic of omeprasol, omeprus, is close by effectiveness to the known drug omeaz.

• Authors: I Iu Kolesnikova, G S Beliaeva, D S Bordin
• Journal: Klinicheskaia meditsina (Klin Med (Mosk)) Vol. 80 Issue 2 Pg. 54-6 ( 2002) ISSN: 0023-2149 [Print] Russia (Federation)
• Vernacular Title: Sutochnoe monitorirovanie vnutrizheludochnoĭ kislotnosti v otsenke éffektivnosti antisekretornoĭ terapii iazvennoĭ bolezni dvenadtsatiperstnoĭ kishki.
• PMID: 11898725 (Publication Type: English Abstract, Journal Article)

Chemical References

• Anti-Ulcer Agents
• Omeprazole

Topics

• Adult
• Anti-Ulcer Agents (therapeutic use)
• Circadian Rhythm (physiology)
• Duodenal Ulcer (diagnosis, drug therapy)
• Female
• Gastric Acidity Determination
• Humans
• Hydrogen-Ion Concentration
• Male
• Omeprazole (therapeutic use)